TAC4 - tachykinin precursor 4 Gene

中文名称：速激肽前体 4

种属: Homo sapiens

同用名: EK; HK1; HK-1; PPT-C

关于 TAC4

功能概要

该基因是神经递质编码基因速激肽家族的成员。速激肽蛋白被切割成小的分泌肽，激活受体蛋白家族的成员。该基因的产物优先激活速激肽受体 1，并被认为调节外周内分泌和旁分泌功能，包括血压、免疫系统和内分泌腺分泌。该基因的产物缺乏在其他速激肽蛋白中发现的双碱基切割位点。因此，体内产生的裂解产物的性质仍有待确定。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2008 年 7 月]

This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted Peptides that activate members of a family of Receptor Proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in Other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]