2. Gene
  3. Plau - plasminogen activator, urokinase Gene

Plau - plasminogen activator, urokinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: UPAM

基因 ID: 25619 | 基因类型: protein coding

关于 Plau

功能概要

Enables peptidase activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; cellular response to staurosporine; and positive regulation of ovulation. Located in extracellular space and membrane. Used to study several diseases, including alcoholic liver cirrhosis; lung disease (multiple); sciatic neuropathy; status epilepticus; and transient cerebral ischemia. Biomarker of brain disease (multiple); end stage renal disease; myocardial infarction; sciatic neuropathy; and thrombosis. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); Quebec platelet disorder; end stage renal disease; lung disease (multiple); and mitral valve prolapse. Orthologous to human PLAU (plasminogen activator, urokinase). [provided by Alliance of Genome Resources, Apr 2022]

Plau 基因产物(1)

mRNA Protein Name
NM_013085.3 NP_037217.3 urokinase-type plasminogen activator precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activity IDA
IDA: 通过直接分析推断
2509088 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IMP
IMP: 通过突变表型推断
15854129 RGD
involved in cellular response to fluid shear stress IEP
IEP: 通过表达模式推断
19166201 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
17953365 RGD
involved in cellular response to hepatocyte growth factor stimulus IEP
IEP: 通过表达模式推断
19834131 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
19490965 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19184369 RGD
involved in cellular response to staurosporine IEP
IEP: 通过表达模式推断
19137075 RGD
involved in embryo implantation IEP
IEP: 通过表达模式推断
15019809 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16899994 RGD
involved in positive regulation of reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
16456094 RGD
involved in positive regulation of smooth muscle cell migration IMP
IMP: 通过突变表型推断
9315743 RGD
involved in regulation of hepatocyte proliferation IMP
IMP: 通过突变表型推断
17587687 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
22592543 RGD
involved in response to hepatocyte growth factor IEP
IEP: 通过表达模式推断
21843593 RGD
involved in response to hyperoxia IEP
IEP: 通过表达模式推断
19099788 RGD
involved in skeletal muscle tissue regeneration IMP
IMP: 通过突变表型推断
12919869 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
17712486 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
10727258 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

urokinase-type plasminogen activator

U-plasminogen activator

Urinary plasminogen activator, urokinase

uPA

urokinase plasminogen activator

重组 Plau 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73561 PLAU/uPA Protein, Rat (HEK293, His) Q3KR76/NP_037217.3 (G20-F432) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10647 PLAU Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plau NCBI NCBI:5328
Macaca fascicularis Plau NCBI NCBI:102135886
Mus musculus Plau NCBI NCBI:18792
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