2. Gene
  3. LRIG1 - leucine rich repeats and immunoglobulin like domains 1 Gene

LRIG1 - leucine rich repeats and immunoglobulin like domains 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富亮氨酸的重复序列和免疫球蛋白样结构域 1

种属: Homo sapiens

同用名: LIG1; LIG-1

基因 ID: 26018 | 基因类型: protein coding

关于 LRIG1

Cytogenetic location: 3p14.1 Genomic coordinates (GRCh38): 3:66,378,797-66,501,121 (from NCBI)

This gene has 9 transcripts (splice variants), 203 orthologues and 22 paralogues. Ubiquitous expression in brain (RPKM 61.1), fat (RPKM 28.0) and 23 other tissues.

功能概要

预计在几个过程的上游或内部起作用，包括神经支配；耳石形态发生；和声音的感官知觉。预测位于质膜中。预计在细胞外基质和细胞外空间中具有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LRIG1 基因产物(7)

mRNA Protein Name
NM_001377344.1 NP_001364273.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 2 precursor
NM_001377345.1 NP_001364274.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 3
NM_001377346.1 NP_001364275.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 3
NM_001377347.1 NP_001364276.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 4
NM_001377348.1 NP_001364277.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 5
NM_001377349.1 NP_001364278.1 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 6
NM_015541.3 NP_056356.2 leucine-rich repeats and immunoglobulin-like domains protein 1 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15282549 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LRIG1 蛋白结构

LRR_8

LRR_8: Leucine rich repeat (71 - 104)

LRR_8

LRR_8: Leucine rich repeat (116 - 175)

LRR_8

LRR_8: Leucine rich repeat (189 - 247)

LRR_8

LRR_8: Leucine rich repeat (308 - 367)

LRR_8

LRR_8: Leucine rich repeat (383 - 441)

LRRCT

LRRCT: Leucine rich repeat C-terminal domain (466 - 490)

I-set

I-set: Immunoglobulin I-set domain (495 - 595)

I-set

I-set: Immunoglobulin I-set domain (599 - 689)

I-set

I-set: Immunoglobulin I-set domain (694 - 780)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1093 a.a.
蛋白主名 其他名称

leucine-rich repeats and immunoglobulin-like domains protein 1

leucine-rich repeat protein LRIG1

重组 LRIG1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77988 LRIG1 Protein, Human (HEK293, His) Q96JA1-1 (A35-S779) ≥95%

关联疾病

疾病名称 别名
Urofacial Syndrome 1

Urofacial Syndrome

Ochoa Syndrome

Hydronephrosis With Peculiar Facial Expression

Ufs

Inverted Smile And Occult Neuropathic Bladder

Partial Facial Palsy With Urinary Abnormalities

UFS1

Urofacial Ochoa'S Syndrome

Urofacial Syndrome Type 1

Facial Palsy, Partial, With Urinary Abnormalities

Hydronephrosis-Inverted Smile

Inverted Smile-Neurogenic Bladder

Hydronephrosis-Inverted Smile Syndrome

Inverted Smile-Neurogenic Bladder Syndrome

Partial Facial Palsy Partial With Urinary Abnormalities

Urologic Diseases
Sebaceous Adenoma

Adenoma Of The Sebaceous Gland

Skin Appendage Sebaceous Adenoma
Sebaceous Gland Neoplasm

Sebaceous Gland Neoplasms

Sebaceous Neoplasm
Hair Follicle Neoplasm

Hair Matrix Neoplasm

Hair Matrix Tumour
Colonic Benign Neoplasm

Colon Neoplasm

Colonic Mass

Colonic Tumor

Neoplasm Of Colon

Neoplasm Of The Colon

Colonic Neoplasms

Colon Cancer

Colon Carcinoma Nos

Colonic Cancer

Metastatic Colon Cancer Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07787 LRIG1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LRIG1 RGD RGD:1306788
Macaca mulatta LRIG1 VGNC VGNC:84156
Canis familiaris LRIG1 VGNC VGNC:42767
Bos taurus LRIG1 VGNC VGNC:30982
Felis catus LRIG1 VGNC VGNC:80612
Mus musculus LRIG1 MGD MGI:107935
Macaca fascicularis LRIG1 NCBI NCBI:102140736
Others LRIG1 NCBI
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