2. Gene
  3. FDCSP - follicular dendritic cell secreted protein Gene

FDCSP - follicular dendritic cell secreted protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：滤泡树突状细胞分泌蛋白

种属: Homo sapiens

同用名: C4orf7; FDC-SP

基因 ID: 260436 | 基因类型: protein coding

关于 FDCSP

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,226,124-70,235,252 (from NCBI)

This gene has 1 transcript (splice variant) and 44 orthologues. Biased expression in salivary gland (RPKM 447.2), lymph node (RPKM 235.7) and 1 other tissue.

功能概要

该基因编码一种在滤泡树突细胞中表达的小分泌蛋白。这种蛋白质特异性结合活化的 B 细胞，并作为抗体反应的调节剂发挥作用。它也被认为通过促进癌细胞迁移和侵袭而促进肿瘤转移。[RefSeq 提供，2011 年 12 月]

This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting Cancer cell migration and invasion. [provided by RefSeq, Dec 2011]

FDCSP 基因产物(1)

mRNA Protein Name
NM_152997.4 NP_694542.1 follicular dendritic cell secreted peptide precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FDCSP 蛋白结构

FDC-SP

FDC-SP: Follicular dendritic cell secreted peptide (18 - 82)

  • 0
  • 85 a.a.
蛋白主名 其他名称

follicular dendritic cell secreted peptide

FDC secreted protein

FDCSP 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FDCSP Q8NFU4 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
种属内
FDCSP Q8NFU4 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
FDCSP Q8NFU4 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属内
FDCSP Q8NFU4 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Follicular Dendritic Cell Sarcoma

Dendritic Cell Sarcoma

Dendritic Cell Sarcoma, Follicular

Follicular Dendritic Cell Tumour

Dendritic Cell Sarcoma, Interdigitating

Dendritic Cell Sarcoma, Not Otherwise Specified
Epidermolysis Bullosa, Junctional 5b, With Pyloric Atresia

Junctional Epidermolysis Bullosa With Pyloric Atresia

Carmi Syndrome

Epidermolysis Bullosa, Junctional, With Pyloric Atresia

Jeb-Pa

JEB5B

Epidermolysis Bullosa Junctionalis With Pyloric Atresia

Aplasia Cutis Congenita With Gastrointestinal Atresia

Epidermolysis Bullosa, Junctional, With Pyloric Atresia And Aplasia Cutis Congenita

Eb-Pa-Acc

Junctional Epidermolysis Bullosa-Pyloric Atresia Syndrome

Jeb With Pyloric Atresia

Epidermolysis Bullosa Letalis, With Pyloric Atresia

Pa-Jeb

Epidermolysis Bullosa With Pyloric Atresia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04851 FDCSP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus FDCSP RGD RGD:1359468
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