1. Gene
  2. DECR2 - 2,4-dienoyl-CoA reductase 2 Gene

DECR2 - 2,4-dienoyl-CoA reductase 2 Gene

中文名称:2,4-二烯酰辅酶 A 还原酶 2

种属: Homo sapiens

同用名: PDCR; SDR17C1

基因 ID: 26063 | 基因类型: protein coding

关于 DECR2

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:401,885-412,482 (from NCBI)

This gene has 17 transcripts (splice variants), 1 gene allele, 200 orthologues and 1 paralogue. Broad expression in kidney (RPKM 18.7), liver (RPKM 15.2) and 25 other tissues.

功能概要

启用 2,4-二烯酰辅酶 A 还原酶 (NADPH) 活性和反式 2-烯酰辅酶 A 还原酶 (NADPH) 活性。参与不饱和脂肪酸的生物合成过程。预测位于过氧化物酶体中。 [由基因组资源联盟提供,2022 年 4 月]

Enables 2,4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

DECR2 基因产物(1)

mRNA Protein Name
NM_020664.4 NP_065715.1 peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

DECR2 蛋白结构

adh_short_C2

adh_short_C2: Enoyl-(Acyl carrier protein) reductase (38 - 271)

  • 0
  • 100
  • 200
  • 292 a.a.
蛋白主名 其他名称

peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

2,4-dienoyl-CoA reductase 2, peroxisomal

DECR2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DECR2 Q9NUI1 WDTC1 Homo sapiens Q8N5D0
Anti Tag CoIP
33961781
种属内
DECR2 Q9NUI1 C14orf119 Homo sapiens Q9NWQ9
Validated Y2H
32296183
种属内
DECR2 Q9NUI1 OSGIN1 Homo sapiens Q9UJX0
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Acute Inflammation Of Lacrimal Passage
Dacryocystitis

Nasolacrimal Sac Infection

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus DECR2 MGD MGI:1347059
Macaca mulatta DECR2 VGNC VGNC:71767
Felis catus DECR2 VGNC VGNC:61423
Bos taurus DECR2 VGNC VGNC:27983
Rattus norvegicus DECR2 RGD RGD:71002
Canis familiaris DECR2 VGNC VGNC:54016