2. Gene
  3. Map2k4 - mitogen-activated protein kinase kinase 4 Gene

Map2k4 - mitogen-activated protein kinase kinase 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MEK4; MKK4; Sek1; JNKK1; Serk1; PRKMK4; MAPKK 4

基因 ID: 26398 | 基因类型: protein coding

关于 Map2k4

功能概要

Predicted to enable ATP binding activity; JUN kinase kinase activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in positive regulation of smooth muscle cell apoptotic process. Acts upstream of or within MAPK cascade; negative regulation of motor neuron apoptotic process; and response to wounding. Predicted to be located in several cellular components, including axon; dendrite cytoplasm; and perikaryon. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in colorectal cancer; ovarian serous carcinoma; pancreatic cancer; respiratory system Cancer (multiple); and urinary bladder Cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Map2k4 基因产物(6)

mRNA Protein Name
NM_001316367.1 NP_001303296.1 dual specificity mitogen-activated protein kinase kinase 4 isoform a
NM_001316368.1 NP_001303297.1 dual specificity mitogen-activated protein kinase kinase 4 isoform c
NM_001316369.1 NP_001303298.1 dual specificity mitogen-activated protein kinase kinase 4 isoform c
NM_001362739.1 NP_001349668.1 dual specificity mitogen-activated protein kinase kinase 4 isoform d
NM_001362740.1 NP_001349669.1 dual specificity mitogen-activated protein kinase kinase 4 isoform d
NM_009157.5 NP_033183.1 dual specificity mitogen-activated protein kinase kinase 4 isoform b
蛋白主名 其他名称

dual specificity mitogen-activated protein kinase kinase 4

C-JUN N-terminal kinase kinase 1

JNK kinase 1

JNK-activating kinase 1

MAP kinase kinase 4

MAPK/ERK kinase 4

SAPK/ERK kinase 1

SAPK/Erk/kinase 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16235 Map2k4 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-159190 HRX-0233 Inhibitor / 否
HY-RS08040 MAP2K4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2k4 NCBI NCBI:6416
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