2. Gene
  3. Nlrx1 - NLR family member X1 Gene

Nlrx1 - NLR family member X1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：NLR 家族成员 X1

种属: Mus musculus

同用名: NOD9

基因 ID: 270151 | 基因类型: protein coding

关于 Nlrx1

Chromosome 9: 44,164,014-44,179,896 reverse strand.GRCm39:CM001002.3

This gene has 6 transcripts (splice variants), 193 orthologues, 22 paralogues and is associated with 13 phenotypes. Ubiquitous expression in colon adult (RPKM 11.8), adrenal adult (RPKM 1.3) and 27 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动。在 I-kappaB 激酶/NF-kappaB 信号的负调节上游或负调节内起作用；细胞因子产生的负调节；防御反应的负调节。位于线粒体中。与人类 NLRX1（NLR 家族成员 X1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of cytokine production; and negative regulation of defense response. Located in mitochondrion. Orthologous to human NLRX1 (NLR family member X1). [provided by Alliance of Genome Resources, Apr 2022]

Nlrx1 基因产物(3)

mRNA Protein Name
NM_178420.3 NP_848507.2 NLR family member X1
NM_001163742.1 NP_001157214.1 NLR family member X1
NM_001163743.1 NP_001157215.1 NLR family member X1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21703540 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of interferon-beta production IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of interleukin-6 production IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of macrophage cytokine production IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of RIG-I signaling pathway IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of innate immune response IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of interferon-beta production IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
21703540 MGI
acts upstream of or within negative regulation of macrophage cytokine production IMP
IMP: 通过突变表型推断
21703540 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Nlrx1 蛋白结构

P-loop_NTPase

P-loop_NTPase: cl38936 (159 - 319)

LRR_RI

LRR_RI: sd00033 (697 - 725)

PPP1R42

PPP1R42: cl42388 (697 - 902)

LRR_RI

LRR_RI: sd00033 (726 - 747)

LRR_RI

LRR_RI: sd00033 (748 - 771)

LRR_RI

LRR_RI: sd00033 (772 - 807)

LRR_RI

LRR_RI: sd00033 (808 - 835)

LRR_RI

LRR_RI: sd00033 (836 - 863)

LRR_RI

LRR_RI: sd00033 (864 - 885)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 975 a.a.
蛋白主名 其他名称

NLR family member X1

nucleotide-binding domain and leucine-rich repeat containing

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-141521 Amelenodor Activator 98.47% Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09365 NLRX1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09366 Nlrx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09367 Nlrx1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nlrx1 NCBI NCBI:79671
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