2. Gene
  3. NLRX1 - NLR family member X1 Gene

NLRX1 - NLR family member X1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NLR 家族成员 X1

种属: Homo sapiens

同用名: NOD5; NOD9; NOD26; DLNB26; CLR11.3

基因 ID: 79671 | 基因类型: protein coding

关于 NLRX1

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:119,168,334-119,184,016 (from NCBI)

This gene has 14 transcripts (splice variants), 193 orthologues and 20 paralogues. Ubiquitous expression in esophagus (RPKM 15.5), skin (RPKM 7.2) and 25 other tissues.

功能概要

该基因编码的蛋白质是 NLR 家族的成员，定位于线粒体外膜。编码的蛋白质是线粒体抗病毒反应的调节剂。已发现该基因的三个转录变体编码相同的蛋白质。[RefSeq 提供，2013 年 8 月]

The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2013]

NLRX1 基因产物(12)

mRNA Protein Name
XM_005271669.2 XP_005271726.1 NLR family member X1 isoform X1
XM_006718904.2 XP_006718967.1 NLR family member X1 isoform X2
XM_047427589.1 XP_047283545.1 NLR family member X1 isoform X3
NM_001282143.2 NP_001269072.1 NLR family member X1 isoform 1 precursor
XM_047427588.1 XP_047283544.1 NLR family member X1 isoform X2
NM_170722.2 NP_733840.1 NLR family member X1 isoform 2 precursor
NM_024618.4 NP_078894.2 NLR family member X1 isoform 1 precursor
XM_011542980.2 XP_011541282.1 NLR family member X1 isoform X1
NM_001282144.2 NP_001269073.1 NLR family member X1 isoform 1 precursor
XM_047427586.1 XP_047283542.1 NLR family member X1 isoform X2
XM_047427587.1 XP_047283543.1 NLR family member X1 isoform X2
NM_001282358.2 NP_001269287.1 NLR family member X1 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18200010 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NLRX1 蛋白结构

NACHT

NACHT: NACHT domain (160 - 320)

LRR_6

LRR_6: Leucine Rich repeat (779 - 799)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 975 a.a.
蛋白主名 其他名称

NLR family member X1

NOD-like receptor X1

caterpiller protein 11.3

nucleotide-binding oligomerization domain protein 26

nucleotide-binding oligomerization domain protein 5

nucleotide-binding oligomerization domain protein 9

nucleotide-binding oligomerization domain, leucine rich repeat containing X1

NLRX1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross NLRX1 Q86UT6 Sarm1 Mus musculus Q6PDS3
Anti Tag CoIP
21903422
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Histiocytic Sarcoma

Malignant Histiocytosis
Mooren'S Ulcer

Mooren Ulcer

Moorens Ulcer
Mitochondrial Complex V Deficiency, Nuclear Type 3

Mitochondrial Complex Iii Deficiency Nuclear Type 5

MC5DN3

Mitochondrial Complex Iii Deficiency, Nuclear Type 5

Mitochondrial Complex V Deficiency Nuclear Type 3

MC3DN5

Mitochondrial Complex V Deficiency, Atp5e Type

Mitochondrial Complex Iii Deficiency, Nuclear 5

Mitochondrial Complex V Deficiency, Nuclear Type 3

Mitochondrial Complex V Deficiency Atp5e Type

Mitochondrial Complex V Deficiency Type 3

Mitochondrial Complex V Deficiency, Nuclear, Type 3
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-141521 Amelenodor Activator 98.47% Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09365 NLRX1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09366 Nlrx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09367 Nlrx1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris NLRX1 VGNC VGNC:43853
Macaca mulatta NLRX1 VGNC VGNC:75283
Bos taurus NLRX1 VGNC VGNC:32122
Mus musculus NLRX1 MGD MGI:2429611
Felis catus NLRX1 VGNC VGNC:63834
Rattus norvegicus NLRX1 RGD RGD:1311293
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