1. Gene
  2. GK2 - glycerol kinase 2 Gene

GK2 - glycerol kinase 2 Gene

中文名称:甘油激酶 2

种属: Homo sapiens

同用名: GKP2; GKTA

基因 ID: 2712 | 基因类型: protein coding

关于 GK2

Cytogenetic location: 4q21.21 Genomic coordinates (GRCh38): 4:79,406,361-79,408,228 (from NCBI)

This gene has 1 transcript (splice variant), 246 orthologues and 6 paralogues.

功能概要

预测启用甘油激酶活性。预计参与多个过程,包括甘油代谢过程; 3-磷酸甘油生物合成过程;和甘油三酯代谢过程。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable glycerol kinase activity. Predicted to be involved in several processes, including glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

GK2 基因产物(1)

mRNA Protein Name
NM_033214.3 NP_149991.2 glycerol kinase 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28852571 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in sperm midpiece IDA
IDA: 通过直接分析推断
28852571 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GK2 蛋白结构

FGGY_N

FGGY_N: FGGY family of carbohydrate kinases, N-terminal domain (14 - 266)

FGGY_C

FGGY_C: FGGY family of carbohydrate kinases, C-terminal domain (275 - 466)

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  • 553 a.a.
蛋白主名 其他名称

glycerol kinase 2

ATP:glycerol 3-phosphotransferase 2

关联疾病

疾病名称 别名
Glycerol Kinase Deficiency

Hyperglycerolemia

GKD

Gk Deficiency

Gk1 Deficiency

Deficiency Of Glycerol Kinase

Isolated Glycerol Kinase Deficiency

Glycerol Kinase Deficiency, Adult Form

Glycerol Kinase Deficiency, Juvenile Form

Deficiency, Glycerol Kinase

Hypoadrenocorticism, Familial

Addison Disease

Primary Adrenocortical Insufficiency

Addison'S Disease

Adrenal Gland Hypofunction

Adrenal Hypoplasia

Adrenal Aplasia

Addison Disease, Chronic Adrenal Insufficiency

Primary Hypoadrenalism

Hypoadrenocorticism Familial

Autoimmune Addison Disease

Autoimmune Adrenalitis

Classic Addison Disease

Primary Addison Disease

Addisons Disease

Addison Disease, Susceptibility To

Autoimmune Primary Adrenal Insufficiency

Addison'S Disease Due To Autoimmunity

Muscular Dystrophy, Duchenne Type

Duchenne Muscular Dystrophy

DMD

Muscular Dystrophy, Duchenne

Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type

Severe Dystrophinopathy, Duchenne Type

Muscular Dystrophy Duchenne

Dystrophy, Muscular, Duchenne Type

Benign Duchenne Muscular Dystrophy

Duchenne Motor Neuron Disease

Duchenne Type Dystrophy

Duchenne-Griesinger Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GK2 VGNC VGNC:57407
Rattus norvegicus GK2 RGD RGD:1303263
Mus musculus GK2 MGD MGI:1329027
Macaca mulatta GK2 VGNC VGNC:106585
Others GK2 NCBI