2. Gene
  3. SULT1C4 - sulfotransferase family 1C member 4 Gene

SULT1C4 - sulfotransferase family 1C member 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：磺基转移酶家族 1C 成员 4

种属: Homo sapiens

同用名: SULT1C; SULT1C2

基因 ID: 27233 | 基因类型: protein coding

关于 SULT1C4

Cytogenetic location: 2q12.3 Genomic coordinates (GRCh38): 2:108,377,954-108,388,989 (from NCBI)

This gene has 3 transcripts (splice variants), 256 orthologues and 12 paralogues. Broad expression in gall bladder (RPKM 13.7), ovary (RPKM 9.3) and 15 other tissues.

功能概要

磺基转移酶催化许多激素、神经递质、药物和异生化合物的硫酸盐结合。这些胞质酶的组织分布和底物特异性不同。家族成员之间的基因结构 (外显子的数量和长度) 相似。该基因编码属于 SULT1 亚家族的蛋白质，负责将磺基部分从 PAPS 转移到含酚化合物。[RefSeq 提供，2008 年 7 月]

Sulfotransferase Enzymes catalyze the sulfate conjugation of many Hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic Enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. [provided by RefSeq, Jul 2008]

SULT1C4 基因产物(2)

mRNA Protein Name
NM_001321770.2 NP_001308699.1 sulfotransferase 1C4 isoform 2
NM_006588.4 NP_006579.2 sulfotransferase 1C4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aryl sulfotransferase activity IDA
IDA: 通过直接分析推断
17425406 GOA
enables sulfotransferase activity IDA
IDA: 通过直接分析推断
20056724 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 3'-phosphoadenosine 5'-phosphosulfate metabolic process IDA
IDA: 通过直接分析推断
23207770 GOA
involved in doxorubicin metabolic process IDA
IDA: 通过直接分析推断
26948952 GOA
involved in ethanol catabolic process IDA
IDA: 通过直接分析推断
23207770 GOA
involved in flavonoid metabolic process IDA
IDA: 通过直接分析推断
28222028 GOA
involved in sulfation IDA
IDA: 通过直接分析推断
20056724 GOA
involved in xenobiotic metabolic process IDA
IDA: 通过直接分析推断
26948952 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
28222028 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SULT1C4 蛋白结构

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (45 - 294)

  • 0
  • 100
  • 200
  • 302 a.a.
蛋白主名 其他名称

sulfotransferase 1C4

ST1C4

重组 SULT1C4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71342 SULT1C4 Protein, Human (His) Q6PD90 (M1-K102) ≥95%

关联疾病

疾病名称 别名
Ectodermal Dysplasia 1, Hypohidrotic, X-Linked

Christ-Siemens-Touraine Syndrome

XHED

Ectodermal Dysplasia 1

Xlhed

Ed1

Cst Syndrome

Ectodermal Dysplasia 1, Hypohidrotic/Hair/Tooth Type, X-Linked

Ectd1

Ectodermal Dysplasia, Anhidrotic, X-Linked

Eda

Eda1

Hed1

Ectodermal Dysplasia 1, Anhidrotic

X-Linked Anhidrotic Ectodermal Dysplasia

X-Linked Hypohidrotic Ectodermal Dysplasia

Hypohidrotic X-Linked Ectodermal Dysplasia

Ectodermal Dysplasia, Hypohidrotic, 1

Hypohidrotic Ectodermal Dysplasia, X-Linked

Anhidrotic Ectodermal Dysplasia X-Linked

Hypohidrotic Ectodermal Dysplasia X-Linked

Ectodermal Dysplasia 1 Hypohidrotic/Hair/Tooth Type X-Linked

Ectodermal Dysplasia Anhidrotic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14018 SULT1C4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SULT1C4 VGNC VGNC:106230
Mus musculus SULT1C4 MGD MGI:102928
Felis catus SULT1C4 VGNC VGNC:65836
Canis familiaris SULT1C4 VGNC VGNC:46978
Others SULT1C4 NCBI
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