1. Gene
  2. CISD3 - CDGSH iron sulfur domain 3 Gene

CISD3 - CDGSH iron sulfur domain 3 Gene

中文名称:CDGSH 铁硫结构域 3

种属: Homo sapiens

同用名: MiNT; Miner2

基因 ID: 284106 | 基因类型: protein coding

关于 CISD3

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:38,730,341-38,735,605 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 94 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 15.7), small intestine (RPKM 14.3) and 25 other tissues.

功能概要

CISD3 是包含 CDGSH 结构域的家族成员,可能在调节电子传输和氧化磷酸化方面发挥作用 (Wiley 等人,2007 [PubMed 17376863]) 。[OMIM 提供,2008 年 4 月]

CISD3 is a member of the CDGSH domain-containing family, which may play a role in regulating electron transport and Oxidative Phosphorylation (Wiley et al., 2007 [PubMed 17376863]).[supplied by OMIM, Apr 2008]

CISD3 基因产物(1)

mRNA Protein Name
NM_001136498.2 NP_001129970.1 CDGSH iron-sulfur domain-containing protein 3, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 2 iron, 2 sulfur cluster binding IDA
IDA: 通过直接分析推断
29259115 GOA
enables metal ion binding IDA
IDA: 通过直接分析推断
29259115 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein maturation by [2Fe-2S] cluster transfer IDA
IDA: 通过直接分析推断
29259115 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
17376863 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CISD3 蛋白结构

zf-CDGSH

zf-CDGSH: Iron-binding zinc finger CDGSH type (44 - 75)

zf-CDGSH

zf-CDGSH: Iron-binding zinc finger CDGSH type (82 - 114)

  • 0
  • 100
  • 127 a.a.
蛋白主名 其他名称

CDGSH iron-sulfur domain-containing protein 3, mitochondrial

mitoNEET related 2

关联疾病

疾病名称 别名
Wolfram Syndrome 2

WFS2

Wolfram Syndrome

Didmoad Syndrome

Didmoad

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Wfs

Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness

Didmoadud

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CISD3 RGD RGD:1559720
Mus musculus CISD3 MGD MGI:101788
Bos taurus CISD3 VGNC VGNC:27373
Canis familiaris CISD3 VGNC VGNC:39280