2. Gene
  3. ENDOV - endonuclease V Gene

ENDOV - endonuclease V Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核酸内切酶 V

种属: Homo sapiens

基因 ID: 284131 | 基因类型: protein coding

关于 ENDOV

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:80,415,167-80,438,086 (from NCBI)

This gene has 30 transcripts (splice variants) and 175 orthologues. Ubiquitous expression in testis (RPKM 3.1), prostate (RPKM 2.3) and 25 other tissues.

功能概要

启用 DNA 结合活性；核糖核酸内切酶活性，产生 5'-磷酸单酯；和单链 RNA 结合活性。预测参与 DNA 修复。位于细胞质应激颗粒和核仁中。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA binding activity; endoribonuclease activity, producing 5'-phosphomonoesters; and single-stranded RNA binding activity. Predicted to be involved in DNA repair. Located in cytoplasmic stress granule and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

ENDOV 基因产物(5)

mRNA Protein Name
NM_001164637.3 NP_001158109.1 endonuclease V isoform 2
NM_001164638.3 NP_001158110.1 endonuclease V isoform 3
NM_001352760.3 NP_001339689.1 endonuclease V isoform 4
NM_001352761.3 NP_001339690.1 endonuclease V isoform 5
NM_173627.5 NP_775898.2 endonuclease V isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
23139746 GOA
enables RNA endonuclease activity, producing 5'-phosphomonoesters IDA
IDA: 通过直接分析推断
3170309 GOA
NOT enables endodeoxyribonuclease activity, producing 5'-phosphomonoesters IDA
IDA: 通过直接分析推断
23139746 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
27573237 GOA
enables single-stranded RNA binding IDA
IDA: 通过直接分析推断
23912683 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23139746 GOA
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
27573237 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
23139746 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ENDOV 蛋白结构

Endonuclease_5

Endonuclease_5: Endonuclease V (45 - 242)

  • 0
  • 100
  • 200
  • 282 a.a.
蛋白主名 其他名称

endonuclease V

hEndoV

关联疾病

疾病名称 别名
Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum

XPV

Xeroderma Pigmentosum Variant Type

Xeroderma Pigmentosum With Normal Dna Repair Rates

Photosensitivity With Defective Dna Synthesis

Xp

De Sanctis-Cacchione Syndrome

Desanctis-Cacchione Syndrome

Xeroderma Pigmentosa

Xerodermic Idiocy

Xeroderma Pigmentosum Variant

Xp - [Xeroderma Pigmentosum]

Atrophoderma Pigmentosum
Cockayne Syndrome B

Cockayne Syndrome Type 2

Cockayne Syndrome, Type B

Cockayne Syndrome Type Ii

CSB

Cockayne Syndrome 2

Cockayne Syndrome Type B

Ckn2

Cockayne Syndrome, Type Ii
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04373 ENDOV Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ENDOV RGD RGD:1562414
Mus musculus ENDOV MGD MGI:2444688
Canis familiaris ENDOV VGNC VGNC:40361
Felis catus ENDOV VGNC VGNC:61860
Bos taurus ENDOV VGNC VGNC:28492
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