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  2. GPR22 - G protein-coupled receptor 22 Gene

GPR22 - G protein-coupled receptor 22 Gene

中文名称:G 蛋白偶联受体 22

种属: Homo sapiens

基因 ID: 2845 | 基因类型: protein coding

关于 GPR22

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:107,470,057-107,477,845 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 226 orthologues and 16 paralogues. Biased expression in heart (RPKM 6.9), brain (RPKM 4.8) and 2 other tissues.

功能概要

该基因是 G 蛋白偶联受体 1 家族的成员,编码一种多通道膜蛋白。[RefSeq 提供,2008 年 7 月]

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008]

GPR22 基因产物(1)

mRNA Protein Name
NM_005295.3 NP_005286.2 G-protein coupled receptor 22
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IMP
IMP: 通过突变表型推断
18539757 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GPR22 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (59 - 367)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 433 a.a.
蛋白主名 其他名称

G-protein coupled receptor 22

probable G-protein coupled receptor 22

关联疾病

疾病名称 别名
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Melas Syndrome

MELAS

Mitochondrial Encephalomyopathy Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode

Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes

Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke

Mitochondrial Encephalomyopathy, Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis And Stroke-Like Episodes

Mitochondrial Encephalomyopathy With Lactic Acidosis And Stroke-Like Episodes Syndrome

Myopathy, Mitochondrial, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GPR22 RGD RGD:1310848
Macaca mulatta GPR22 VGNC VGNC:73129
Canis familiaris GPR22 VGNC VGNC:41426
Mus musculus GPR22 MGD MGI:1920260
Felis catus GPR22 VGNC VGNC:67421
Bos taurus GPR22 VGNC VGNC:29580