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  3. EPHA10 - EPH receptor A10 Gene

EPHA10 - EPH receptor A10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：EPH 受体 A10

种属: Homo sapiens

基因 ID: 284656 | 基因类型: protein coding

关于 EPHA10

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:37,713,880-37,765,120 (from NCBI)

This gene has 11 transcripts (splice variants), 110 orthologues and 53 paralogues. Biased expression in testis (RPKM 7.0), colon (RPKM 2.9) and 7 other tissues.

功能概要

Ephrin 受体是受体酪氨酸激酶 (RTK) 的最大亚家族，它们的 ephrin 配体是细胞间通讯的重要介质，可调节神经元和上皮细胞的细胞附着、形状和移动性 (Aashheim 等人，2005 [PubMed 15777695] ) .有关 Eph 受体和肝配蛋白的其他背景，请参阅 MIM 179610。[OMIM 提供，2008 年 3 月]

Ephrin receptors, the largest subfamily of Receptor Tyrosine Kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph Receptors and Ephrins.[supplied by OMIM, Mar 2008]

EPHA10 基因产物(2)

mRNA Protein Name
NM_001099439.2 NP_001092909.1 ephrin type-A receptor 10 isoform 3 precursor
NM_173641.3 NP_775912.2 ephrin type-A receptor 10 isoform 2 precursor

EPHA10 蛋白结构

Ephrin_lbd

Ephrin_lbd: Ephrin receptor ligand binding domain (35 - 211)

fn3

fn3: Fibronectin type III domain (339 - 432)

fn3

fn3: Fibronectin type III domain (464 - 533)

EphA2_TM

EphA2_TM: Ephrin type-A receptor 2 transmembrane domain (567 - 642)

Pkinase_Tyr

Pkinase_Tyr: Protein tyrosine kinase (646 - 900)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (934 - 994)

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  • 1008 a.a.
蛋白主名 其他名称

ephrin type-A receptor 10

EphA10s protein

重组 EPHA10 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77929 EPHA10 Protein, Human (HEK293, His) Q5JZY3-1 (E34-A565) ≥95%

关联疾病

疾病名称 别名
Hypogonadotropic Hypogonadism 6 With Or Without Anosmia

HH6

Kallmann Syndrome 6

Kal6

Hypogonadotropic Hypogonadism, Type 6 With/Without Anosmia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04425 EPHA10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus EPHA10 MGD MGI:3586824
Felis catus EPHA10 VGNC VGNC:107531
Macaca mulatta EPHA10 VGNC VGNC:99905
Rattus norvegicus EPHA10 RGD RGD:1562679
Bos taurus EPHA10 VGNC VGNC:28533
Macaca fascicularis EPHA10 NCBI
Others EPHA10 NCBI
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