1. Gene
  2. FRYL - FRY like transcription coactivator Gene

FRYL - FRY like transcription coactivator Gene

中文名称:FRY 样转录共激活因子

种属: Homo sapiens

同用名: MOR2; AF4p12; KIAA0826

基因 ID: 285527 | 基因类型: protein coding

关于 FRYL

This gene has 21 transcripts (splice variants), 233 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 15.9), lymph node (RPKM 5.8) and 24 other tissues.

功能概要

预计参与细胞形态发生和神经元投射发育。预计在细胞皮层和极化生长部位活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in cell morphogenesis and neuron projection development. Predicted to be active in cell cortex and site of polarized growth. [provided by Alliance of Genome Resources, Apr 2022]

FRYL 基因产物(1)

mRNA Protein Name
NM_015030.2 NP_055845.1 protein furry homolog-like
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FRYL 蛋白结构

MOR2-PAG1_N

MOR2-PAG1_N: Cell morphogenesis N-terminal (117 - 649)

MOR2-PAG1_mid

MOR2-PAG1_mid: Cell morphogenesis central region (1167 - 1322)

MOR2-PAG1_mid

MOR2-PAG1_mid: Cell morphogenesis central region (1364 - 1411)

MOR2-PAG1_mid

MOR2-PAG1_mid: Cell morphogenesis central region (1593 - 1652)

MOR2-PAG1_mid

MOR2-PAG1_mid: Cell morphogenesis central region (1739 - 1861)

MOR2-PAG1_C

MOR2-PAG1_C: Cell morphogenesis C-terminal (1999 - 2257)

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  • 3013 a.a.
蛋白主名 其他名称

protein furry homolog-like

ALL1-fused gene from chromosome 4p12 protein

FRYL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FRYL O94915 HOMER3 Homo sapiens Q9NSC5
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta FRYL VGNC VGNC:72803
Mus musculus FRYL MGD MGI:1919563
Canis familiaris FRYL VGNC VGNC:40989
Felis catus FRYL VGNC VGNC:62371
Rattus norvegicus FRYL RGD RGD:1311309
Bos taurus FRYL VGNC VGNC:29123