2. Gene
  3. Fis1 - fission, mitochondrial 1 Gene

Fis1 - fission, mitochondrial 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ttc11

基因 ID: 288584 | 基因类型: protein coding

关于 Fis1

功能概要

Enables identical protein binding activity. Involved in several processes, including cellular response to thapsigargin; mitochondrial fragmentation involved in apoptotic process; and positive regulation of mitochondrial fission. Located in mitochondrion and peroxisomal membrane. Is integral component of mitochondrial outer membrane. Biomarker of dental fluorosis; fatty liver disease; kidney failure (multiple); myocardial infarction; and rhinitis. Orthologous to human FIS1 (fission, mitochondrial 1). [provided by Alliance of Genome Resources, Apr 2022]

Fis1 基因产物(2)

mRNA Protein Name
NM_001105919.2 NP_001099389.1 mitochondrial fission 1 protein isoform 1
NM_001401051.1 NP_001387980.1 mitochondrial fission 1 protein isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
27684054 RGD
involved in cellular response to lipid IEP
IEP: 通过表达模式推断
18006463 RGD
involved in cellular response to peptide IDA
IDA: 通过直接分析推断
24103571 RGD
involved in cellular response to toxic substance IEP
IEP: 通过表达模式推断
26732598 RGD
involved in mitochondrial fragmentation involved in apoptotic process IMP
IMP: 通过突变表型推断
18940801 RGD
involved in positive regulation of mitochondrial fission IMP
IMP: 通过突变表型推断
15979461 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
18940801 RGD
involved in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
17443673 RGD
involved in response to flavonoid IEP
IEP: 通过表达模式推断
24637344 RGD
involved in response to fluoride IEP
IEP: 通过表达模式推断
23007560 RGD
involved in response to hypobaric hypoxia IEP
IEP: 通过表达模式推断
24361501 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
24943897 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
25336449 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
15979461 RGD
located in peroxisomal membrane IDA
IDA: 通过直接分析推断
16107562 RGD
located in peroxisome IDA
IDA: 通过直接分析推断
14561759 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mitochondrial fission 1 protein

TPR repeat protein 11

fis1 homolog

fission 1 (mitochondrial outer membrane) homolog

rFis1

tetratricopeptide repeat domain 11

tetratricopeptide repeat protein 11

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10368 P110 heptapeptide Inhibitor 99.84% 否
HY-P2280 TAT-P110 Inhibitor 99.87% 否
HY-155656 Anti-inflammatory agent 49 Inhibitor 98.26% 否
HY-RS04951 FIS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fis1 NCBI NCBI:51024
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