2. Gene
  3. GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

GRID1 - glutamate ionotropic receptor delta type subunit 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：谷氨酸离子型受体 δ 型亚基 1

种属: Homo sapiens

同用名: GluD1; GluD1-b

基因 ID: 2894 | 基因类型: protein coding

关于 GRID1

Cytogenetic location: 10q23.1-q23.2 Genomic coordinates (GRCh38): 10:85,599,552-86,366,795 (from NCBI)

This gene has 3 transcripts (splice variants), 329 orthologues and 17 paralogues. Biased expression in brain (RPKM 6.7), thyroid (RPKM 3.7) and 12 other tissues.

功能概要

该基因编码谷氨酸受体通道的一个亚基。这些通道介导中枢神经系统中的大部分快速兴奋性突触传递，并在突触可塑性中发挥关键作用。[RefSeq 提供，2009 年 1 月]

This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009]

GRID1 基因产物(1)

mRNA Protein Name
NM_017551.3 NP_060021.1 glutamate receptor ionotropic, delta-1 precursor

GRID1 蛋白结构

ANF_receptor

ANF_receptor: Receptor family ligand binding region (40 - 397)

SBP_bac_3

SBP_bac_3: Bacterial extracellular solute-binding proteins, family 3 (446 - 805)

Lig_chan

Lig_chan: Ligand-gated ion channel (564 - 842)

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  • 1009 a.a.
蛋白主名 其他名称

glutamate receptor ionotropic, delta-1

gluR delta-1 subunit

GRID1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GRID1 Q9ULK0 HBB Homo sapiens P68871
Anti Tag CoIP
28514442
种属内
GRID1 Q9ULK0 HBB Homo sapiens P68871
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Chromosome 17q21.31 Duplication Syndrome

17q21.31 Microduplication Syndrome

Trisomy 17q21.31

Dup(17)(Q21.31)
Rett Syndrome

Atypical Rett Syndrome

RTT

Rett Disorder

Rts

Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use

Rett Syndrome, Preserved Speech Variant

Rett Syndrome, Atypical

Rett'S Disorder

Rett Syndrome Variant

Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome

Cerebroatrophic Hyperammonemia

Rett Like Syndrome

Rett'S Syndrome

Atypical Rtt

Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use

Rett Syndrome Preserved Speech Variant

Rett Syndrome Zappella Variant

Rett Syndrome, Zappella Variant
Diaphragmatic Eventration
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05795 GRID1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus GRID1 VGNC VGNC:55986
Rattus norvegicus GRID1 RGD RGD:68366
Macaca mulatta GRID1 VGNC VGNC:73275
Felis catus GRID1 VGNC VGNC:67464
Mus musculus GRID1 MGD MGI:95812
Canis familiaris GRID1 VGNC VGNC:51898
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