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  2. Nuak2 - NUAK family kinase 2 Gene

Nuak2 - NUAK family kinase 2 Gene

中文名称:NUAK 家族激酶 2

种属: Rattus norvegicus

同用名: Snark; UV126; 1200013b22rik

基因 ID: 289419 | 基因类型: protein coding

关于 Nuak2

Primary_assembly 13: 43,753,832-43,770,604 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 213 orthologues, 26 paralogues and is associated with 4 phenotypes. Biased expression in Kidney (RPKM 251.3), Adrenal (RPKM 38.5) and 6 other tissues.

功能概要

该基因编码的蛋白可启动 ATP 绑定活动;镁离子结合活性;和蛋白丝氨酸/苏氨酸激酶活性。参与细胞对葡萄糖饥饿和蛋白质磷酸化的反应。预计在细胞质中有活性。该基因的人类直系同源物与无脑畸形有关。与人 NUAK2(NUAK 家族激酶 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in cellular response to glucose starvation and protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human NUAK2 (NUAK family kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Nuak2 基因产物(2)

mRNA Protein Name
NM_001007617.1 NP_001007618.1 NUAK family SNF1-like kinase 2
NM_001007617.1 NP_001007618.1 NUAK family SNF1-like kinase 2

Nuak2 蛋白结构

PKc_like

PKc_like: cl21453 (52 - 306)

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  • 500
  • 630 a.a.
蛋白主名 其他名称

NUAK family SNF1-like kinase 2

NUAK family, SNF1-like kinase, 2

SNF1MP kinase-related kinase

SNF1MP-activated protein kinase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nuak2 NCBI NCBI:81788