1. Gene
  2. Car4 - carbonic anhydrase 4 Gene

Car4 - carbonic anhydrase 4 Gene

中文名称:碳酸酐酶 4

种属: Rattus norvegicus

同用名: Ca4

基因 ID: 29242 | 基因类型: protein coding

关于 Car4

Primary_assembly 10: 69,827,945-69,836,501 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 333 orthologues, 16 paralogues and is associated with 6 phenotypes. Biased expression in Lung (RPKM 349.5), Kidney (RPKM 191.9) and 3 other tissues.

功能概要

该基因编码的蛋白可启动碳酸盐脱水酶活性。参与动物器官发育;对类固醇激素的反应;和对外来刺激的反应。位于顶端质膜;肌膜;和肌浆网。该基因的人类直系同源物与色素性视网膜炎有关。与人 CA4(碳酸酐酶 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables carbonate dehydratase activity. Involved in animal organ development; response to steroid hormone; and response to xenobiotic stimulus. Located in apical plasma membrane; sarcolemma; and sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA4 (Carbonic Anhydrase 4). [provided by Alliance of Genome Resources, Apr 2022]

Car4 基因产物(1)

mRNA Protein Name
NM_019174.3 NP_062047.1 carbonic anhydrase 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbonate dehydratase activity IDA
IDA: 通过直接分析推断
1533109 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
10569998 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16144999 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
8675662 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
8911968 RGD
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
8911968 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Car4 蛋白结构

alpha_CA_IV_XV_like

alpha_CA_IV_XV_like: cd03117 (46 - 279)

  • 0
  • 100
  • 200
  • 309 a.a.
蛋白主名 其他名称

carbonic anhydrase 4

CA-IV

carbonate dehydratase IV

carbonic anhydrase IV