2. Gene
  3. Esrra - estrogen related receptor, alpha Gene

Esrra - estrogen related receptor, alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：雌激素相关受体， α

种属: Rattus norvegicus

同用名: Errra; ERRalpha

基因 ID: 293701 | 基因类型: protein coding

关于 Esrra

Primary_assembly 1: 204,104,101-204,114,268 reverse strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 175 orthologues, 8 paralogues and is associated with 15 phenotypes. Biased expression in Heart (RPKM 313.6), Muscle (RPKM 294.8) and 9 other tissues.

功能概要

该基因编码的蛋白可启动序列特异性 DNA 结合活性。参与多个过程，包括成骨细胞分化的调节；破骨细胞分化的调节；和对雌二醇的反应。位于核内。与人类 ESRRA（雌激素相关受体 α）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables sequence-specific DNA binding activity. Involved in several processes, including regulation of osteoblast differentiation; regulation of osteoclast differentiation; and response to estradiol. Located in nucleus. Orthologous to human ESRRA (estrogen related receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Esrra 基因产物(1)

mRNA Protein Name
NM_001008511.2 NP_001008511.2 steroid hormone receptor ERR1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
20215575 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cartilage development IMP
IMP: 通过突变表型推断
17170100 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17170100 RGD
involved in positive regulation of cellular response to insulin stimulus IMP
IMP: 通过突变表型推断
20215575 RGD
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
11381083 RGD
involved in regulation of ossification IMP
IMP: 通过突变表型推断
12193582 RGD
involved in regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
11381083 RGD
involved in regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
12193582 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
15458797 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Esrra 蛋白结构

NR_DBD_ERR

NR_DBD_ERR: cd07170 (72 - 167)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (195 - 418)

  • 0
  • 100
  • 200
  • 300
  • 422 a.a.
蛋白主名 其他名称

steroid hormone receptor ERR1

ERR-alpha

nuclear receptor subfamily 3 group B member 1

orphan nuclear receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04537 ESRRA Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04538 Esrra Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04539 Esrra Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Esrra NCBI NCBI:2101
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z