1. Gene
  2. DKK1 - Dkk1 dickkopf WNT signaling pathway inhibitor 1 Gene

DKK1 - Dkk1 dickkopf WNT signaling pathway inhibitor 1 Gene

种属: Rattus norvegicus

基因 ID: 293897 | 基因类型: protein coding

关于 DKK1

功能概要

Predicted to enable co-receptor binding activity; low-density lipoprotein particle receptor binding activity; and receptor antagonist activity. Involved in negative regulation of ossification and positive regulation of neuron death. Located in extracellular space. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf Wnt signaling pathway inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

DKK1 基因产物(1)

mRNA Protein Name
NM_001106350.1 NP_001099820.1 dickkopf-related protein 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of ossification IMP
IMP: 通过突变表型推断
21773994 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
22009597 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dickkopf-related protein 1

dickkopf 1 homolog

dickkopf homolog 1

dickkopf-like protein 1

重组 DKK1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73305 DKK-1 Protein, Rat (HEK293, His, solution) A6I0Z0/NP_001099820.1 (T32-H270) ≥95%
HY-P73305A DKK-1 Protein, Rat (HEK293, C-His) A6I0Z0/NP_001099820.1 (T32-H270) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens DKK1 NCBI NCBI:22943
Macaca fascicularis DKK1 NCBI NCBI:102123735
Mus musculus DKK1 NCBI NCBI:13380
Macaca mulatta DKK1 NCBI NCBI:702997