2. Gene
  3. Tgfbr3 - transforming growth factor beta receptor 3 Gene

Tgfbr3 - transforming growth factor beta receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：转化生长因子 β 受体 3

种属: Rattus norvegicus

同用名: betaglycan

基因 ID: 29610 | 基因类型: protein coding

关于 Tgfbr3

Primary_assembly 14: 2,489,397-2,663,341 forward strand.mRatBN7.2:CM026987.1

This gene has 1 transcript (splice variant), 203 orthologues, 2 paralogues and is associated with 5 phenotypes. Biased expression in Adrenal (RPKM 475.), Lung (RPKM 174.) and 9 other tissues.

功能概要

该基因编码的蛋白可启动多种功能，包括激活素结合活动；生长因子结合活性；和肝素结合活性。参与多个过程，包括动物器官再生；转化生长因子β受体信号通路的调节；和转化生长因子β受体复合物组装。位于细胞质中；细胞外基质；和细胞外空间。是质膜的组成部分。受体复合体的一部分。与人 TGFBR3（转化生长因子 β 受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including activin binding activity; growth factor binding activity; and heparin binding activity. Involved in several processes, including animal organ regeneration; regulation of transforming growth factor beta receptor signaling pathway; and transforming growth factor beta receptor complex assembly. Located in cytoplasm; extracellular matrix; and extracellular space. Is integral component of plasma membrane. Part of receptor complex. Orthologous to human TGFBR3 (transforming growth factor beta receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tgfbr3 基因产物(1)

mRNA Protein Name
NM_017256.1 NP_058952.1 transforming growth factor beta receptor type 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables activin binding IDA
IDA: 通过直接分析推断
12385827 RGD
enables fibroblast growth factor binding IDA
IDA: 通过直接分析推断
1556106 RGD
enables heparin binding IDA
IDA: 通过直接分析推断
8106553 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7852346 RGD
enables transforming growth factor beta binding IDA
IDA: 通过直接分析推断
1657407 RGD
contributes to transforming growth factor beta binding IPI
IPI: 通过物理相互作用推断
7852346 RGD
enables transforming growth factor beta receptor activity, type III IDA
IDA: 通过直接分析推断
8106553 RGD
enables transforming growth factor beta receptor binding IDA
IDA: 通过直接分析推断
8106553 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
9699514 RGD
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
10746731 RGD
involved in positive regulation of transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
8106553 RGD
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
12385827 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
12183510 RGD
involved in transforming growth factor beta receptor complex assembly IMP
IMP: 通过突变表型推断
8106553 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
2592419 RGD
located in membrane IDA
IDA: 通过直接分析推断
8106553 RGD
part of receptor complex IDA
IDA: 通过直接分析推断
7852346 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Tgfbr3 蛋白结构

ZP

ZP: smart00241 (455 - 732)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 853 a.a.
蛋白主名 其他名称

transforming growth factor beta receptor type 3

TGF-beta receptor type 3

TGF-beta receptor type III

TGFR-3

transforming growth factor, beta receptor III

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14450 TGFBR3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14451 Tgfbr3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14452 Tgfbr3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14453 TGFBR3L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tgfbr3 NCBI NCBI:7049
Mus musculus Tgfbr3 NCBI NCBI:21814
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