1. Gene
  2. Slc16a7 - solute carrier family 16 member 7 Gene

Slc16a7 - solute carrier family 16 member 7 Gene

中文名称:溶质载体家族 16 成员 7

种属: Rattus norvegicus

同用名: Mct2

基因 ID: 29735 | 基因类型: protein coding

关于 Slc16a7

Primary_assembly 7: 61,051,167-61,154,994 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 254 orthologues, 13 paralogues and is associated with 1 phenotype. Biased expression in Kidney (RPKM 249.5), Liver (RPKM 113.8) and 8 other tissues.

功能概要

预计该基因编码的蛋白可启动乳酸跨膜转运蛋白活性和丙酮酸跨膜转运蛋白活性。参与质膜乳酸转运。位于细胞质和质膜中。活跃于多种细胞成分,包括 Schaffer 侧支 - CA1 突触;海马苔藓纤维至 CA3 突触;和浦肯野细胞突触的平行纤维。是突触后密度膜的组成部分。与人类 SLC16A7 同源(溶质载体家族 16 成员 7)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable lactate transmembrane transporter activity and pyruvate transmembrane transporter activity. Involved in plasma membrane lactate transport. Located in cytoplasm and plasma membrane. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and parallel fiber to Purkinje cell synapse. Is integral component of postsynaptic density membrane. Orthologous to human SLC16A7 (solute carrier family 16 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc16a7 基因产物(1)

mRNA Protein Name
NM_017302.2 NP_058998.2 monocarboxylate transporter 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15917240 RGD
enables symporter activity IDA
IDA: 通过直接分析推断
10417314 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in plasma membrane lactate transport IDA
IDA: 通过直接分析推断
19929853 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
15749979 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15749979 RGD
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
15749979 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
15749979 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
15749979 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Slc16a7 蛋白结构

2A0113

2A0113: TIGR00892 (20 - 435)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 489 a.a.
蛋白主名 其他名称

monocarboxylate transporter 2

MCT 2

solute carrier family 16 (monocarboxylate transporter), member 7

solute carrier family 16 (monocarboxylic acid transporters), member 7

solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc16a7 NCBI NCBI:9194