Pik3cg - phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Gene

中文名称：磷脂酰肌醇 4 ,5-二磷酸 3-激酶，催化亚基 γ

种属: Rattus norvegicus

同用名: Pi3k

关于 Pik3cg

功能概要

该基因编码的蛋白可启动 1-磷脂酰肌醇-3-激酶活性。参与多个过程，包括肝细胞凋亡过程；甘油三酯分解代谢过程的负调节；和磷脂酰肌醇磷酸盐的生物合成过程。磷脂酰肌醇 3-激酶复合物的一部分。用于研究肝硬化。糖尿病视网膜病变的生物标志物。该基因的人类直系同源物与自闭症和猪流感有关。与人 PIK3CG（磷脂酰肌醇 4,5-二磷酸 3-激酶催化亚基 γ）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including hepatocyte apoptotic process; negative regulation of triglyceride catabolic process; and phosphatidylinositol phosphate biosynthetic process. Part of phosphatidylinositol 3-kinase complex. Used to study liver cirrhosis. Biomarker of diabetic retinopathy. Human ortholog(s) of this gene implicated in autistic disorder and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]