1. Gene
  2. Mknk2 - MAPK interacting serine/threonine kinase 2 Gene

Mknk2 - MAPK interacting serine/threonine kinase 2 Gene

中文名称:MAPK 相互作用的 丝氨酸/苏氨酸激酶 2

种属: Rattus norvegicus

基因 ID: 299618 | 基因类型: protein coding

关于 Mknk2

Primary_assembly 7: 9,039,728-9,050,827 forward strand.mRatBN7.2:CM026980.1

This gene has 2 transcripts (splice variants), 224 orthologues, 6 paralogues and is associated with 1 phenotype. Biased expression in Muscle (RPKM 36.3), Spleen (RPKM 34.2) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动;钙调蛋白结合活性;和蛋白丝氨酸/苏氨酸激酶活性。预计参与多个过程,包括细胞对含砷物质的反应;细胞内信号转导;和蛋白质磷酸化。预计在没有配体的情况下作用于外在凋亡信号通路的上游或内部。预计位于核体。预计在细胞质和细胞核中有活性。与人 MKNK2(MAPK 相互作用的丝氨酸/苏氨酸激酶 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ATP binding activity; Calmodulin binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to arsenic-containing substance; intracellular signal transduction; and protein phosphorylation. Predicted to act upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nuclear body. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK2 (MAPK interacting serine/threonine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mknk2 基因产物(1)

mRNA Protein Name
NM_001011985.2 NP_001011985.1 MAP kinase-interacting serine/threonine-protein kinase 2

Mknk2 蛋白结构

PKc_like

PKc_like: cl21453 (80 - 367)

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  • 459 a.a.
蛋白主名 其他名称

MAP kinase-interacting serine/threonine-protein kinase 2

MAP kinase signal-integrating kinase 2

MAP kinase-interacting serine/threonine kinase 2

MAPK signal-integrating kinase 2

mnk2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mknk2 NCBI NCBI:2872