S1pr3 - sphingosine-1-phosphate receptor 3 Gene

中文名称：1-磷酸鞘氨醇受体 3

种属: Rattus norvegicus

同用名: Edg3; lpb3; Edg3l

关于 S1pr3

功能概要

预测该基因编码的蛋白编码的蛋白可启动 G 蛋白偶联受体活性和整合素结合活性。预计参与腺苷酸环化酶激活G蛋白偶联受体信号通路；内皮屏障建立的负调控；和代谢过程的调节。预测作用于多个过程的上游或内部，包括 Notch 信号通路；腺苷酸环化酶抑制G蛋白偶联受体信号通路；和调节白细胞介素-1 β 的产生。预计是膜的组成部分。预计在细胞质和质膜中有活性。与人 S1PR3（1-磷酸鞘氨醇受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity and Integrin binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of establishment of endothelial barrier; and regulation of metabolic process. Predicted to act upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3). [provided by Alliance of Genome Resources, Apr 2022]