2. Gene
  3. Angptl3 - angiopoietin-like 3 Gene

Angptl3 - angiopoietin-like 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: hypl

基因 ID: 30924 | 基因类型: protein coding

关于 Angptl3

功能概要

This gene encodes a member of the angiopoietin-like family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may inhibit triglyceride metabolism. Homozygous knockout mice for this gene exhibit reduced plasma lipid concentrations, including reduced plasma triglyceride concentrations, and enhanced activity of Enzymes involved in triglyceride metabolism. [provided by RefSeq, Aug 2015]

Angptl3 基因产物(1)

mRNA Protein Name
NM_013913.4 NP_038941.1 angiopoietin-related protein 3 preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme inhibitor activity IDA
IDA: 通过直接分析推断
12097324 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acylglycerol homeostasis IMP
IMP: 通过突变表型推断
17110602 MGI
involved in artery morphogenesis IMP
IMP: 通过突变表型推断
12671033 MGI
involved in cholesterol homeostasis IMP
IMP: 通过突变表型推断
17110602 MGI
involved in negative regulation of phospholipase activity IMP
IMP: 通过突变表型推断
17110602 MGI
involved in phospholipid homeostasis IMP
IMP: 通过突变表型推断
17110602 MGI
involved in triglyceride homeostasis IMP
IMP: 通过突变表型推断
19542565 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
23918928 MGI
located in cell surface IDA
IDA: 通过直接分析推断
23918928 MGI
located in early endosome IDA
IDA: 通过直接分析推断
23918928 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

angiopoietin-related protein 3

angiopoietin-like protein 3

重组 Angptl3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7504 ANGPTL3/Angiopoietin-like 3 Protein, Mouse (HEK293, His) Q9R182 (S17-T206) ≥95%

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-153497A Vupanorsen sodium Inhibitor 92.29% Phase 2
HY-153497 Vupanorsen Inhibitor 92.29% Phase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Angptl3 NCBI NCBI:27329
Macaca fascicularis Angptl3 NCBI NCBI:102136264
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