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  2. HK3 - hexokinase 3 Gene

HK3 - hexokinase 3 Gene

中文名称:己糖激酶 3

种属: Homo sapiens

同用名: HXK3; HKIII

基因 ID: 3101 | 基因类型: protein coding

关于 HK3

Cytogenetic location: 5q35.2 Genomic coordinates (GRCh38): 5:176,880,869-176,899,346 (from NCBI)

This gene has 6 transcripts (splice variants), 129 orthologues and 4 paralogues. Biased expression in bone marrow (RPKM 50.3), spleen (RPKM 14.0) and 3 other tissues.

功能概要

己糖激酶磷酸化葡萄糖以产生 6-磷酸葡萄糖,这是大多数葡萄糖代谢途径的第一步。该基因编码己糖激酶 3。与己糖激酶 1 和 2 类似,该变构酶被其产物 6-磷酸葡萄糖抑制。[RefSeq 提供,2009 年 4 月]

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes Hexokinase 3. Similar to hexokinases 1 and 2, this allosteric Enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]

HK3 基因产物(1)

mRNA Protein Name
NM_002115.3 NP_002106.2 hexokinase-3

HK3 蛋白结构

Hexokinase_1

Hexokinase_1: Hexokinase (28 - 231)

Hexokinase_2

Hexokinase_2: Hexokinase (237 - 475)

Hexokinase_1

Hexokinase_1: Hexokinase (480 - 675)

Hexokinase_2

Hexokinase_2: Hexokinase (677 - 916)

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  • 923 a.a.
蛋白主名 其他名称

hexokinase-3

ATP:D-hexose 6-phosphotransferase

重组 HK3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74881 HK3/Hexokinase-3 Protein, Human (sf9, His-GST) P52790 (M1-V923) ≥95%

直系同源

种属 基因名 来源 基因 ID
Canis familiaris HK3 VGNC VGNC:41700
Felis catus HK3 VGNC VGNC:67581
Rattus norvegicus HK3 RGD RGD:2798
Bos taurus HK3 VGNC VGNC:29866
Macaca mulatta HK3 VGNC VGNC:73476
Mus musculus HK3 MGD MGI:2670962
Others HK3 NCBI