1. Gene
  2. Pak5 - p21 (RAC1) activated kinase 5 Gene

Pak5 - p21 (RAC1) activated kinase 5 Gene

中文名称:p21 (RAC1) 激活激酶 5

种属: Rattus norvegicus

同用名: Pak7; PAK-5; PAK-7

基因 ID: 311450 | 基因类型: protein coding

关于 Pak5

Primary_assembly 3: 123,396,497-123,703,930 reverse strand.mRatBN7.2:CM026976.1

This gene has 1 transcript (splice variant), 214 orthologues, 36 paralogues and is associated with 3 phenotypes. Restricted expression toward (RPKM 12.5).

功能概要

预测该基因编码的蛋白可启动蛋白质丝氨酸/苏氨酸激酶活性。预计参与细胞内信号转导;蛋白质磷酸化;和 MAPK 级联的调节。预计在学习或记忆的上游或之内起作用;运动行为;和外源性凋亡信号通路的负调控。预测位于线粒体和核质中。预计在细胞质和突触中活跃。与人 PAK5(p21 (RAC1) 激活激酶 5)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; protein phosphorylation; and regulation of MAPK cascade. Predicted to act upstream of or within learning or memory; locomotory behavior; and negative regulation of extrinsic apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and synapse. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Pak5 基因产物(1)

mRNA Protein Name
NM_001107781.1 NP_001101251.1 serine/threonine-protein kinase PAK 5

Pak5 蛋白结构

CRIB_PAK_like

CRIB_PAK_like: cd01093 (8 - 54)

STKc_PAK5

STKc_PAK5: cd06658 (424 - 715)

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  • 718 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase PAK 5

p21 (CDKN1A)-activated kinase 7

p21 (RAC1) activated kinase 7

p21 protein (Cdc42/Rac)-activated kinase 7

p21-activated kinase 5

p21-activated kinase 7

serine/threonine-protein kinase PAK 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pak5 NCBI NCBI:57144