1. Gene
  2. Car9 - carbonic anhydrase 9 Gene

Car9 - carbonic anhydrase 9 Gene

中文名称:碳酸酐酶 9

种属: Rattus norvegicus

同用名: Ca9

基因 ID: 313495 | 基因类型: protein coding

关于 Car9

Primary_assembly 5: 57,763,206-57,769,838 forward strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 283 orthologues, 16 paralogues and is associated with 22 phenotypes. Biased expression in Uterus (RPKM 9.7), Muscle (RPKM 6.3) and 9 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动碳酸脱水酶活性。参与对缺氧的反应;对睾酮的反应;和对外来刺激的反应。位于基底外侧质膜。该基因的人类直系同源物与乙型肝炎和肾细胞癌有关。与人 CA9(碳酸酐酶 9)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable carbonate dehydratase activity. Involved in response to hypoxia; response to testosterone; and response to xenobiotic stimulus. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in hepatitis B and renal cell carcinoma. Orthologous to human CA9 (Carbonic Anhydrase 9). [provided by Alliance of Genome Resources, Apr 2022]

Car9 基因产物(1)

mRNA Protein Name
NM_001107956.1 NP_001101426.1 carbonic anhydrase 9 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to hypoxia IEP
IEP: 通过表达模式推断
18071747 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
18180313 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17280655 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
9024293 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Car9 蛋白结构

alpha_CA

alpha_CA: cl00012 (127 - 369)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 437 a.a.
蛋白主名 其他名称

carbonic anhydrase 9

carbonic anhydrase IX