1. Gene
  2. CYP27C1 - cytochrome P450 family 27 subfamily C member 1 Gene

CYP27C1 - cytochrome P450 family 27 subfamily C member 1 Gene

中文名称:细胞色素 P450 家族 27 亚家族 C 成员 1

种属: Homo sapiens

基因 ID: 339761 | 基因类型: protein coding

关于 CYP27C1

This gene has 3 transcripts (splice variants), 171 orthologues and 3 paralogues. Biased expression in skin (RPKM 1.8), urinary bladder (RPKM 0.5) and 11 other tissues.

功能概要

该基因编码细胞色素 P450 酶超家族的成员。细胞色素 P450 蛋白是单加氧酶,可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. [provided by RefSeq, Jul 2008]

CYP27C1 基因产物(3)

mRNA Protein Name
NM_001001665.4 NP_001001665.3 cytochrome P450 27C1 isoform 1
NM_001367501.1 NP_001354430.1 cytochrome P450 27C1 isoform 1
NM_001367502.1 NP_001354431.1 cytochrome P450 27C1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 11-cis retinal binding IDA
IDA: 通过直接分析推断
27059013 GOA
enables 11-cis-retinal 3,4-desaturase activity IDA
IDA: 通过直接分析推断
27059013 GOA
enables all-trans retinal 3,4-desaturase activity IDA
IDA: 通过直接分析推断
27059013 GOA
enables all-trans retinal binding IDA
IDA: 通过直接分析推断
27059013 GOA
enables all-trans retinoic acid 3,4-desaturase activity IDA
IDA: 通过直接分析推断
27059013 GOA
enables all-trans retinol 3,4-desaturase activity IDA
IDA: 通过直接分析推断
27059013 GOA
enables all-trans-retinol binding IDA
IDA: 通过直接分析推断
27059013 GOA
enables retinoic acid binding IDA
IDA: 通过直接分析推断
27059013 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in retinal metabolic process IDA
IDA: 通过直接分析推断
27059013 GOA
involved in retinoic acid metabolic process IDA
IDA: 通过直接分析推断
27059013 GOA
involved in retinol metabolic process IDA
IDA: 通过直接分析推断
27059013 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CYP27C1 蛋白结构

p450

p450: Cytochrome P450 (2 - 366)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

cytochrome P450 27C1

all-trans retinol 3,4-desaturase

关联疾病

疾病名称 别名
Keratomalacia

Vitamin A Deficiency

Night Blindness

Retinol Deficiency

Xerotic Keratitis

VAD

Vitamin A

Hypovitaminosis A

Bitot Spots

Bitot Spots In The Young Child

Conjunctival Xerosis With Bitot'S Spots

Vitamin A Deficiency With Cornea Xerosis

Vitamin A Deficiency With Cornea Ulceration Or Xerosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma