UNCX - UNC homeobox Gene

中文名称：UNC 同源框

种属: Homo sapiens

同用名: UNCX4.1

关于 UNCX

功能概要

该基因编码参与体细胞发生和神经发生的同源框转录因子，并且是中轴骨骼特定元素的维持和分化所必需的。该基因还在控制下丘脑神经元与垂体元件连接的发展中发挥作用，使中枢神经元能够到达外周血液循环并输送控制外周功能的激素。该基因的表达与急性髓性白血病的频率增加有关。[RefSeq 提供，2017 年 7 月]

This gene encodes a homeobox transcription factor that is involved in somitogenesis and neurogenesis and is required for the maintenance and differentiation of specific elements of the axial skeleton. This gene also plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and deliver Hormones that control peripheral functions. The expression of this gene is associated with an increased frequency of acute myeloid leukemia. [provided by RefSeq, Jul 2017]