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  2. CD300E - CD300e molecule Gene

CD300E - CD300e molecule Gene

中文名称:CD300e 分子

种属: Homo sapiens

同用名: CLM2; CLM-2; IREM2; PIgR2; IREM-2; PIgR-2; CD300LE; CMRF35-A5

基因 ID: 342510 | 基因类型: protein coding

关于 CD300E

Cytogenetic location: 17q25.1 Genomic coordinates (GRCh38): 17:74,609,885-74,623,738 (from NCBI)

This gene has 2 transcripts (splice variants), 66 orthologues and 13 paralogues. Biased expression in appendix (RPKM 19.2), bone marrow (RPKM 15.3) and 4 other tissues.

功能概要

该基因编码在骨髓细胞上表达的细胞表面蛋白 CD300 糖蛋白家族的成员。该蛋白与 TYRO 蛋白酪氨酸激酶结合蛋白相互作用,被认为是一种激活受体。[RefSeq 提供,2012 年 11 月]

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012]

CD300E 基因产物(1)

mRNA Protein Name
NM_181449.3 NP_852114.2 CMRF35-like molecule 2 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20959446 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CD300E 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (45 - 135)

  • 0
  • 100
  • 200
  • 232 a.a.
蛋白主名 其他名称

CMRF35-like molecule 2

CD300 antigen-like family member E

CD300E 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CD300E Q496F6 CTXN3 Homo sapiens Q4LDR2
Validated Y2H
32296183
Intra CD300E Q496F6 STX8 Homo sapiens Q9UNK0
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 CD300E 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76223 CD300e Protein, Human (HEK293, Fc) Q496F6 (L18-H173) ≥95%

关联疾病

疾病名称 别名
Tungiasis

Tunga Penetrans Infestation

Chigger Flea

S Penetrans

Sarcopsylla Penetrans

T Penetrans

Tunga Penetrans

Sand-Flea Infestation

Jiggers Infestation

Chigoe Infestation

Jigger Disease

Amelogenesis Imperfecta, Type Ia

Amelogenesis Imperfecta Type 1a

AI1A

Amelogenesis Imperfecta, Hypoplastic Type Ia

Amelogenesis Imperfecta Type Ia

Amelogenesis Imperfecta Hypoplastic Type Ia

Amelogenesis Imperfecta 1a

Myeloid Leukemia Associated With Down Syndrome
Lice Infestation

Pediculosis

Louse Infestation

Mixed Pediculosis

Lice Infestations

Infestation By Pediculus

Mixed Pediculosis Infestation

Pediculosis + Lice

Pediculosis And Phthirus Infection

Pediculosis And Phthirus Infections

Pediculosis And Phthirus Infestation

Infestation By Anoplura

Pediculus Infestation

Lice Nos

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CD300E VGNC VGNC:38947
Mus musculus CD300E MGD MGI:2387602
Macaca mulatta CD300E VGNC VGNC:84878
Bos taurus CD300E VGNC VGNC:57137
Rattus norvegicus CD300E RGD RGD:1585137
Others CD300E NCBI