1. Gene
  2. FCRL6 - Fc receptor like 6 Gene

FCRL6 - Fc receptor like 6 Gene

中文名称:Fc 受体样 6

种属: Homo sapiens

同用名: FcRH6

基因 ID: 343413 | 基因类型: protein coding

关于 FCRL6

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,800,512-159,816,257 (from NCBI)

This gene has 7 transcripts (splice variants), 149 orthologues and 17 paralogues. Broad expression in spleen (RPKM 6.7), lung (RPKM 2.6) and 14 other tissues.

功能概要

启用 MHC II 类蛋白结合活性和蛋白磷酸酶结合活性。预测参与细胞表面受体信号通路。位于质膜外侧。 [由基因组资源联盟提供,2022 年 4 月]

Enables MHC class II protein binding activity and protein Phosphatase binding activity. Predicted to be involved in cell surface receptor signaling pathway. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FCRL6 基因产物(2)

mRNA Protein Name
NM_001004310.3 NP_001004310.2 Fc receptor-like protein 6 isoform 1 precursor
NM_001284217.2 NP_001271146.1 Fc receptor-like protein 6 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables MHC class II protein binding IDA
IDA: 通过直接分析推断
20519654 GOA
enables phosphatase binding IPI
IPI: 通过物理相互作用推断
20933011 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
20933011 GOA
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
20933011 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
17213291 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
18991291 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FCRL6 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (22 - 89)

Ig_2

Ig_2: Immunoglobulin domain (112 - 199)

Ig_3

Ig_3: Immunoglobulin domain (206 - 280)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 434 a.a.
蛋白主名 其他名称

Fc receptor-like protein 6

Fc receptor-like protein 7

FCRL6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FCRL6 Q6DN72 GALNT15 Homo sapiens Q8N3T1
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 FCRL6 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71565 FCRL6 Protein, Human (His) Q6DN72-1 (L20-W307) ≥95%

关联疾病

疾病名称 别名
Clear Cell Adenoma
Breast Medullary Carcinoma

Medullary Breast Carcinoma

Medullary Breast Carcinoma With Lymphoid Stroma

Medullary Carcinoma Of Breast

Severe Combined Immunodeficiency

Scid

Severe Combined Immunodeficiency Disease

Combined T And B Cell Inborn Immunodeficiency

Immunodeficiency, Severe Combined

Scid - [Severe Combined Immunodeficiencies]

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus FCRL6 VGNC VGNC:55190
Rattus norvegicus FCRL6 RGD RGD:1563939
Macaca mulatta FCRL6 VGNC VGNC:72602
Mus musculus FCRL6 MGD MGI:3618339
Others FCRL6 NCBI