Pik3c2a - phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Gene

中文名称：磷脂酰肌醇 4-磷酸 3-激酶，催化亚基 2 型 α

种属: Rattus norvegicus

关于 Pik3c2a

功能概要

预计该基因编码的蛋白具有网格蛋白结合活性和磷脂酰肌醇 3-激酶活性。预计参与多个过程，包括磷脂酰肌醇 3-激酶信号传导；磷脂酰肌醇-3-磷酸生物合成过程；和参与发芽血管生成的细胞迁移的正调节。预测作用于自噬体组织的上游或内部；细胞对饥饿的反应；和锌离子跨膜转运的负调节。预计位于几种细胞成分中，包括网格蛋白包被的囊泡；核质；和跨高尔基网络。预计是磷脂酰肌醇 3-激酶复合物的一部分。预计在细胞质和质膜中有活性。与人 PIK3C2A（磷脂酰肌醇 4-磷酸 3-激酶催化亚基 2 型 α）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable clathrin binding activity and phosphatidylinositol 3-kinase activity. Predicted to be involved in several processes, including phosphatidylinositol 3-kinase signaling; phosphatidylinositol-3-phosphate biosynthetic process; and positive regulation of cell migration involved in sprouting angiogenesis. Predicted to act upstream of or within autophagosome organization; cellular response to starvation; and negative regulation of zinc ion transmembrane transport. Predicted to be located in several cellular components, including clathrin-coated vesicle; nucleoplasm; and trans-Golgi network. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha). [provided by Alliance of Genome Resources, Apr 2022]