1. Gene
  2. PIK3C2A - phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Gene

PIK3C2A - phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Gene

中文名称:磷脂酰肌醇 4-磷酸 3-激酶催化亚基 2 型 α

种属: Homo sapiens

同用名: CPK; OCSKD; PI3-K-C2A; PI3K-C2alpha; PI3K-C2-alpha; PI3-K-C2(ALPHA)

基因 ID: 5286 | 基因类型: protein coding

关于 PIK3C2A

Cytogenetic location: 11p15.1 Genomic coordinates (GRCh38): 11:17,086,575-17,207,986 (from NCBI)

This gene has 6 transcripts (splice variants), 222 orthologues, 9 paralogues and is associated with 2 phenotypes. Ubiquitous expression in thyroid (RPKM 18.0), testis (RPKM 13.1) and 25 other tissues.

功能概要

该基因编码的蛋白质属于磷酸肌醇 3-激酶 (PI3K) 家族。 PI3-激酶在涉及细胞增殖、致癌转化、细胞存活、细胞迁移和细胞内蛋白质运输的信号通路中发挥作用。该蛋白质包含脂质激酶催化结构域以及 C 末端 C2 结构域,这是 II 类 PI3 激酶的特征。 C2 结构域充当钙依赖性磷脂结合基序,介导蛋白质向膜的易位,并且还可以介导蛋白质-蛋白质相互作用。这种蛋白质的 PI3 激酶活性对纳摩尔水平的抑制剂 wortmanin 不敏感。这种蛋白质被证明能够被胰岛素激活,并可能参与整合素依赖性信号传导。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by Insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]

PIK3C2A 基因产物(6)

mRNA Protein Name
NM_001321378.2 NP_001308307.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 1
XM_047427128.1 XP_047283084.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X2
NM_001321380.2 NP_001308309.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 2
NM_002645.4 NP_002636.2 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 1
XM_047427127.1 XP_047283083.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1
NM_001386870.1 NP_001373799.1 phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 3

PIK3C2A 蛋白结构

PI3K_rbd

PI3K_rbd: PI3-kinase family, ras-binding domain (413 - 511)

PI3K_C2

PI3K_C2: Phosphoinositide 3-kinase C2 (704 - 842)

PI3Ka

PI3Ka: Phosphoinositide 3-kinase family, accessory domain (PIK domain) (869 - 1039)

PI3_PI4_kinase

PI3_PI4_kinase: Phosphatidylinositol 3- and 4-kinase (1134 - 1346)

PX

PX: PX domain (1424 - 1533)

C2

C2: C2 domain (1575 - 1661)

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  • 1686 a.a.
蛋白主名 其他名称

phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

C2-containing phosphatidylinositol kinase

phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha

phosphoinositide 3-kinase-C2-alpha

phosphoinositide-3-kinase, class 2, alpha polypeptide

ptdIns-3-kinase C2 subunit alpha

关联疾病

疾病名称 别名
Acute Anterolateral Myocardial Infarction

Acute Myocardial Infarction Of Anterolateral Wall

Muscular Dystrophy, Duchenne Type

Duchenne Muscular Dystrophy

DMD

Muscular Dystrophy, Duchenne

Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type

Severe Dystrophinopathy, Duchenne Type

Muscular Dystrophy Duchenne

Dystrophy, Muscular, Duchenne Type

Benign Duchenne Muscular Dystrophy

Duchenne Motor Neuron Disease

Duchenne Type Dystrophy

Duchenne-Griesinger Disease

Endocarditis
Necrotizing Fasciitis

Fasciitis, Necrotizing

Acute Myocardial Infarction

Cardiac Attack

Heart Attack

Exanthem

Exanthema

Rash

Rashes

Pyomyositis

Tropical Pyomyositis

Myositis Purulenta Tropica

Myositis Tropicans

Pm

Suppurative Myositis

Purulent Myositis

Gas Gangrene

Myonecrosis

Gas Bacillus Infection

Gas Gangrene Due To Clostridia

Clostridial Myonecrosis

Clostridial Cellulitis

Muscular Lipidosis

Lipid Storage Myopathy

Posteroinferior Myocardial Infarction
Strabismus

Strabismus, Susceptibility To

Strabismus, Susceptibility To, 1

Strabismus 1

Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease

Autosomal Recessive Polycystic Kidney Disease

Arpkd

Polycystic Kidney Disease, Autosomal Recessive

Polycystic Kidney And Hepatic Disease 1

Pkhd1

PKD4

Polycystic Kidney Disease 4 With Or Without Hepatic Disease

Polycystic Kidney Disease, Infantile, Type I

Polycystic Kidney Disease, Infantile Type

Polycystic Kidney, Autosomal Recessive

Pkd3, Formerly

Polycystic Kidney Disease 4, With Or Without Hepatic Disease

Arpkd/Chf

Ar-Pkd

Polycystic Kidney Disease 4, With Or Without Polycystic Liver Disease

Infantile Polycystic Kidney Disease Type I

Pkd3

Kidney, Polycystic, Disease, Type 4, With/Without Hepatic Disease

Polycystic Kidney Disease 3, Autosomal Dominant

Ectopic Pregnancy

Eccyesis

Pregnancy Ectopic

Pregnancy, Ectopic

Ectopic Pregnancies

Extrauterine Gestation Or Pregnancy

Extrauterine Pregnancy

Ep - [Ectopic Pregnancy]

Ectopic Mole

Aborted Ectopic Pregnancy

Ruptured Ectopic Pregnancy

Miyoshi Muscular Dystrophy

Distal Myopathy

Distal Muscular Dystrophy

Miyoshi Myopathy

Distal Myopathies

Dystrophy, Muscular, Miyoshi

Myopathy, Distal

Distal Muscular Dystrophies

Hemopneumothorax

Haemopneumothorax

Muscle Tissue Disease
Quadriplegia

Tetraplegia

Tetraplegias

Co-Trimoxazole Allergy

Bactrim Allergy

Cotrimoxazol Allergy

Tmp/Smx Allergy

Trimethoprim/Sulfamethoxazole Allergy

Extrinsic Cardiomyopathy
Inflammatory And Toxic Neuropathy
Erysipelas
Compartment Syndrome

Compartment Syndromes

Compartmental Syndrome

Legionellosis

Legionella Infection

Pontiac Fever

Legionnaires' Disease

Infection By Legionella Pneumophilia

Legionella Pneumophila Infection

Sarcoid Meningitis

Meningitis In Sarcoidosis

Kidney Disease

Renal Failure

Kidney Failure

Kidney Diseases

Nephropathy

Abnormality Of The Kidney

Impaired Renal Function Disease

Renal Anomaly

Kidney Dysfunction

Renal Disease

Nephropathies

Renal Failure Adverse Event

Abnormal Renal Function

Rectum Neuroendocrine Neoplasm

Neuroendocrine Tumor Of Rectum

Neuroendocrine Tumor Of The Rectum

Net Of The Rectum

Rectal Net

Rectal Neuroendocrine Tumor

Rectal Neuroendocrine Neoplasm

Myopathy

Muscular Diseases

Myopathies

Aspiration Pneumonia

Pneumonia, Aspiration

Pneumonia Aspiration

Aspiration Pneumonitis

Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Congenital Anomaly Of Heart

Heart Defect

Heart Malformation

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure

Hypokalemia

Potassium Deficiency

Potassium Deficiency Disorder

Hypopotassemia

Potassium

Potassium [K] Deficiency

Hypokalaemic Syndrome

Hypopotassaemia

Hypopotassaemia Syndrome

Hypokalaemic

Potassium Depletion

Disseminated Intravascular Coagulation

Defibrination Syndrome

Dic

Diffuse Or Disseminated Intravascular Coagulation

Fibrinolytic Purpura

Consumption Coagulopathy

Diffuse Intravascular Coagulation

Dic - [Disseminated Intravascular Coagulation]

Disseminated Intravascular Coagulopathy

Fibrinolysis Nos

Thrombolytic Purpura

Muscular Dystrophy, Becker Type

Becker Muscular Dystrophy

BMD

Benign Pseudohypertrophic Muscular Dystrophy

Benign Congenital Myopathy

Becker Dystrophinopathy

Becker'S Muscular Dystrophy

Muscular Dystrophy, Pseudohypertrophic Progressive, Becker Type

Muscular Dystrophy Pseudohypertrophic Progressive, Becker Type

Muscular Dystrophy Becker

Dystrophy, Muscular, Becker Type

Dystrophinopathy

Becker Dystrophy

Becker Type Dystrophy

Bmd - [Becker Muscular Dystrophy]

Diabetes Mellitus, Ketosis-Prone

Diabetic Ketoacidosis

KPD

Diabetes Mellitus, Ketosis-Prone, Susceptibility To

Ketosis-Prone Diabetes Mellitus

Diabetes Mellitus, Insulin-Dependent

Diabetic Ketoacidosis Nos

Dka - [Diabetic Ketoacidosis] Nos

Dka - [Diabetic Ketoacidosis] Without Coma

Dka - [Diabetic Ketoacidosis] With Coma

Muscular Disease
Dermatomyositis

Amyopathic Dermatomyositis

Dermatopolymyositis

Adult Dermatomyositis

Polymyositis With Skin Involvement

Adult Type Dermatomyositis

Petges-Clejat Syndrome

Posterior Myocardial Infarction
Myocardial Infarction

Heart Attack

Myocardial Infarction, Susceptibility To

Myocardial Infarction 1

Myocardial Infarction, Protection Against

Myocardial Infarction, Decreased Susceptibility To

Myocardial Infarction, Decreased

Myocardial Infarct

MCI1

Premature Myocardial Infarction

Myocardial Infarction, Susceptibility To, Type 1

Toxoplasmosis

Disseminated Toxoplasmosis

Multisystemic Disseminated Toxoplasmosis

Acquired Toxoplasmosis

Toxoplasmosis Disease Or Disorder

Infection By Toxoplasma Gondii

Toxoplasmal

Toxoplasma

Myringitis Bullosa Hemorrhagica

Bullous Myringitis

Cutis Laxa, Autosomal Recessive, Type Iiia

ARCL3A

De Barsy Syndrome A

Aldh18a1-Related De Barsy Syndrome

Progeroid Syndrome Of De Barsy

Autosomal Recessive Cutis Laxa Type Iiia

P5cs Deficiency

De Barsy Syndrome

Cutis Laxa, Corneal Clouding, And Mental Retardation

Delta-1-Pyrroline 5-Carboxylate Synthetase Deficiency

Neurocutaneous Syndrome, Bicknell Type

Cutis Laxa Corneal Clouding Mental Retardation

Progeroid Syndrome De Barsy Type

Cutis Laxa, Autosomal Recessive, 3a

Cutis Laxa Autosomal Recessive Type Iiia

Developmental Delay-Choreoathetosis-Joint Dislocation-Lax Skin

Neurocutaneous Syndrome Bicknell Type

Corneal Clouding Cutis Laxa Mental Retardation

Osteogenesis Imperfecta, Type Xviii

OI18

Osteogenesis Imperfecta Type 18

Osteogenesis Imperfecta, Type 18

Osteogenesis Imperfecta 18

Patent Foramen Ovale

Atrial Septal Defect Within Oval Fossa

Foramen Ovale Patent

Ostium Secundum Atrial Septal Defect

Atrial Septal Defect, Ostium Secundum Type

Foramen Ovale, Patent

Defect, Patent Or Persistent, Ostium Secundum

Ostium Secundum Type Atrial Septal Defect

Persistent Ostium Secundum

Asd Ostium Secundum Type

Ostium Secundum Asd

Osasd

Asd, Ostium Secundum Type

Pfo - [Patent Foramen Ovale]

Open Foramen Ovale

Open Oval Foramen

Persistent Foramen Ovale

Secundum Atrial Septal Defect

Toxic Myocarditis
Anterior Compartment Syndrome
Pneumonia

Acute Pneumonia

Pneumonias

Infectious Pneumonia

Pn - [Pneumonia]

Lobar Pneumonia Nos

Multifocal Pneumonia

Orthostatic Pneumonia

Pneumonia Nos

Chronic Pneumonia Nos

Atypical Pneumonia

Passive Pneumonia

Purulent Pneumonia

Interstitial Lobar Pneumonia

Pneumonia, Unspecified

Pneumonia Due To Chlamydia

Pneumonia Due To Chlamydia Pneumoniae

Pneumonia Due To E. Coli

Escherichia Coli Lobar Pneumonia

Pneumonia Due To H. Influenzae

Pneumonia Due To Hemophilus Influenzae

Bronchopneumonia Due To H. Influenzae

Haemophilus Influenzae Lobar Pneumonia

Bronchopneumonia Due To Hemophilus Influenzae

Pseudomonal Pneumonia

Pseudomonas Pneumonia

Pseudomonas Lobar Pneumonia

Staphylococcal Pneumonia

Staphylococcus Pneumonia

Acute Staphylococcal Pneumonia

Staphylococcal Double Pneumonia

Staphylococcal Lobar Pneumonia

Staphylococcal Purulent Pneumonia

Staphylococcal Bronchopneumonia

Pneumococcal Pneumonia

Pneumococcus Pneumonia

Bronchopneumonia Due To S. Pneumoniae

Pneumococcal Lobar Pneumonia

Streptococcal Pneumoniae Pneumonia

Streptococcus Pneumoniae Lobar Pneumonia

Pyemic Pneumococcal Embolism With Pneumonia

Bronchopneumonia Due To Streptococcus Pneumoniae

Pneumonia Due To Streptococcus, Group B

Group B Streptococcal Pneumonia

Adenovirus Pneumonia

Adenoviral Pneumonia

Adenovirus Viral Pneumonia

Pneumonia Respiratory Syncytial Viral

Parainfluenza Viral Pneumonia

Parainfluenzal Pneumonia

Parainfluenza Virus Pneumonia

Human Metapneumovirus Pneumonia

Human Metapneumovirus Infection Resulting In Pneumonia

Pneumocystis Pneumonia

Plasma Cells Pneumonia

Neuroleptic Malignant Syndrome
Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Muscular Dystrophy

Muscular Dystrophies

Congenital Md

Congenital Muscular Dystrophy

Cmd

Mdc

Dystrophy, Muscular

Gower'S Muscular Dystrophy

Progressive Musclular Dystrophy

Pseudohypertrophic Atrophy

Pseudohypertrophic Muscle Paralysis

Pseudohypertrophic Muscular Atrophy

Pseudohypertrophic Muscular Dystrophy

Pseudohypertrophic Paralysis

Pseudomuscular Hypertrophy

Childhood Type Dermatomyositis

Juvenile Dermatomyositis

Juvenile Dm

Childhood Dermatomyositis

Amyopathic Dermatomyositis

Adm

Dermatomyositis Sine Myositis

Dermatomyositis, Childhood Type

Coronary Artery Vasospasm

Coronary Vasospasm

Coronary Artery Spasm

Myotonic Dystrophy 1

Myotonic Dystrophy

Dystrophia Myotonica

Steinert Disease

Myotonic Dystrophy Type 1

Myotonia Atrophica

DM1

Congenital Myotonic Dystrophy

Myotonia Dystrophica

Steinert Myotonic Dystrophy

Dystrophia Myotonica 1

Dm

Steinert'S Disease

Steinert Myotonic Dystrophy Syndrome

Myotonic Dystrophy Of Steinert

Dystrophia Myotonica Type 1

Myotonic Dystrophy Congenital

Dystrophy, Myotonic, Type 1

Dm - [Dystrophia Myotonica]

Myotonic Muscular Dystrophy

Dengue Disease

Dengue Fever

Dengue

Df

Dengue Shock Syndrome

Dengue Virus Infection

Breakbone Fever

Classic Dengue

Classical Dengue

Dengue Hemorrhagic Fever

Hemorrhagic Dengue

Philippine Hemorrhagic Fever

Singapore Hemorrhagic Fever

Thai Hemorrhagic Fever

Severe Dengue

Dengue Fever Without Warning Signs

Dengue Haemorrhagic Fever Grade 1

Dengue Haemorrhagic Fever Without Warning Signs

Bangkok Haemorrhagic Fever

Singapore Haemorrhagic Fever

Thailand Haemorrhagic Fever

Southeast Asia Haemorrhagic Fever

Dhf -[Dengue Haemorrhagic Fever]

Dengue Fever With Warning Signs

Dengue Haemorrhagic Fever With Warning Signs

Dengue Haemorrhagic Fever Grade 2

Philippine Haemorrhagic Fever

Spastic Paraplegia 9b, Autosomal Recessive

SPG9B

Autosomal Recessive Complex Spastic Paraplegia Type 9b

Hereditary Spastic Paraplegia 9b

Autosomal Recessive Spastic Paraplegia 9b

Autosomal Recessive Spastic Paraplegia Type 9b

Ar-Spg9b

Metabolic Acidosis
Left Bundle Branch Hemiblock

Left Bundle Branch Block

Left Bundle-Branch Block

Angina Pectoris

Prinzmetal'S Variant Angina

Prinzmetal Angina

Variant Angina

Angina

Angina Inversa

Prinzmetal'S Angina

Coronary Artery Vasospasm

Angina Pectoris, Variant

Variant Angina Pectoris

Vasospastic Angina

Angor Pectoris

Anginal Syndrome

Ischaemic Chest Pain

Angina Pectoris Syndrome

Angina Syndrome

Cardiac Angina Syndrome

Ap - [Angina Pectoris]

Angina Nos

Ap - [Angina Pectoris] Syndrome

Ischaemic Heart Disease With Angina

Heart Angina

Chest Angina

Angina Attack

Anginal Cardiopathy

Coronary Pain Nos

Exophthalmic Ophthalmoplegia
Coronary Stenosis

Coronary Artery Stenosis

Sarcocystosis

Sarcosporidiosis

Sarcosporidiasis

Crimean-Congo Hemorrhagic Fever

Crimean Hemorrhagic Fever

Cchf

Congo Hemorrhagic Fever

Hemorrhagic Fever, Crimean

Chf Congo Virus

Congo-Crimean Hemorrhagic Fever

Congo Fever

Hemorrhagic Fever Crimean-Congo

Cchf - [Crimean-Congo Haemorrhagic Fever]

Kara Mikh Typhoid Fever

Xīnjiāng Haemorrhagic Fever

Pericardium Disease
Malignant Hyperthermia

Anesthesia Related Hyperthermia

Malignant Hyperpyrexia Due To Anesthesia

Hyperpyrexia, Malignant

Hyperthermia, Malignant

Malignant Hyperpyrexia

Mhs

Malignant Fever

Lateral Myocardial Infarction
Mutism
Myoglobinuria
Myxedema
Speech Disorder

Speech Disorders

Echolalia
Pulmonary Edema
Anteroseptal Myocardial Infarction
Ornithosis

Psittacosis

Chlamydial Pneumonia

Chlamydia Psittaci Infection

Chlamydia Psittaci

Hypothyroidism

Thyroid Diseases

Thyroid Deficiency

Thyroid Insufficiency

Dysfunction Thyroid

Thyroid Disease

Thyroid Dysfunction

Acute Kidney Failure

Acute Renal Failure

Renal Failure Acute

Acute Kidney Injury

Kidney Failure, Acute

Pre-Renal Acute Kidney Injury

Nontraumatic Acute Kidney Injury

Aki - [Acute Kidney Injury]

Arf - [Acute Kidney Failure]

Acute Kidney Disease

Acute Kidney Impairment

Acute Ischaemic Renal Failure

Acute Hypoxic Kidney Failure

Acute Kidney Shutdown

Acute Renal Oedema

Acute Renal Impairment

Acute Kidney Collapse

Acute Necrotising Kidney

Acute Renal Suppression

Lipoprotein Quantitative Trait Locus

Coronary Artery Disease

Coronary Artery Disease, Susceptibility To

Coronary Artery Anomaly

Myocardial Ischemia

Congenital Anomaly Of Coronary Artery

Coronary Arteriosclerosis

Coronary Disease

Coronary Heart Disease

Coronary Artery Disorder

LPAQTL

Lpa Deficiency, Congenital

Coronary Artery Abnormality

Coronary Artery Anomaly, Congenital

Chd

Coronary Syndrome

Congenital Malformations Of Coronary Vessels

Malformation Of Coronary Vessels

Congenital Coronary Artery Anomaly

Congenital Coronary Artery Deformity

Congenital Coronary Artery Disorder

Abnormal Coronary Artery

Congenital Coronary Artery Malposition

Congenital Coronary Disease

Congenital Anomaly Of Coronary Arteries

Isolated Elevated Serum Creatine Phosphokinase Levels

Elevated Serum Cpk

Idiopathic Hyperckemia

Isolated Hyperckemia

Elevated Serum Creatine Phosphokinase

H-Ck

Idiopathic Persistent Elevation Of Serum Creatine Kinase

Cardiogenic Shock

Shock Cardiogenic

Shock, Cardiogenic

Granulomatous Myositis
Ischemia

Acute Coronary Syndrome

Metabolic Crises, Recurrent, With Rhabdomyolysis, Cardiac Arrhythmias, And Neurodegeneration

Metabolic Encephalomyopathic Crises, Recurrent, With Rhabdomyolysis, Cardiac Arrhythmias, And Neurodegeneration

MECRCN

Rhabdomyolysis

Cardiac Tamponade

Pericardial Tamponade

Rose'S Tamponade

Diabetes Mellitus

Diabetes

Status Asthmaticus

Asthma With Status Asthmaticus

Severe Asthma Attack

Legionnaire Disease

Legionnaires' Disease

Legionnaires Disease

Legionnaire Disease, Susceptibility To

Legionella

Legionella Pneumonia

Infection By Legionella Pneumophilia

Legionnaire'S Disease

Legionellosis

Legionaire Disease, Susceptibility To

Legionnaires Pneumonia

Bacterial Meningitis

Meningitis, Bacterial

Meningitis Bacterial

Bm - [Bacterial Meningitis]

Leptomeningitis Bacterial

Pachymeningitis Bacterial

Arachnoiditis Bacterial

Creatine Phosphokinase, Elevated Serum

Hyperckemia, Idiopathic

Cpk, Elevated Serum

Hyperckmia

HYPCK

Oculoskeletodental Syndrome

OCSKD

Cataracts, Early-Onset, With Skeletal And Dental Anomalies

Oculocerebrodental Syndrome

Oculo-Cerebro-Dental Syndrome

Breast Juvenile Papillomatosis

Juvenile Papillomatosis Of The Breast

Hypertension, Essential

Essential Hypertension

Hypertension

High Blood Pressure

Hypertension, Essential, Susceptibility To

Hypertensive Disease

Primary Hypertension

EHT

Hypertension, Salt-Sensitive Essential, Susceptibility To

Hyperpiesia

Idiopathic Hypertension

Hypertensive Disorder

Hypertension, Essential, Susceptibility To, 3

Hypertension, Essential 3

Hypertension, Essential, Salt-Sensitive

Hypertension, Essential, Susceptibility To, 6

Hypertension, Essential 6

Hypertension, Salt-Sensitive Essential

Hypertension, Susceptibility To

Hypertension, Essential, Susceptibility To, 4

Hypertension, Essential 4

Hypertension, Essential, Susceptibility To, 2

Hypertension, Essential 2

Hypertension, Essential, Susceptibility To, 1

Hypertension, Essential 1

Hypertension, Essential, Susceptibility To, 5

Hypertension, Essential 5

Htn

Vascular Hypertensive Disorder

Systemic Primary Arterial Hypertension

Hbp - [High Blood Pressure]

Systemic Arterial Hypertensive Disorder

Elevated Blood Pressure

Arterial Hypertension Nos

Hypertension Nos

Benign Hypertension

Systemic Arterial Hypertension

Systemic Hypertension

Artery Htn

Benign Htn

Vascular Htn

Vascular Hypertension

Cholesterol Hypertension

Cholesterol Htn

Idiopathic Htn

Malignant Hypertension

Malignant Htn

Raised Blood Pressure

Cardiovascular Hypertension

Primary Htn - [Hypertension]

High Arterial Tension

High Blood Pressure Disorder

Ht - [Hypertension]

Htn - [Hypertension]

Hypertensive Vascular Disease

Hypertensive Vascular Degeneration

Lung Mixed Small Cell And Squamous Cell Carcinoma

Combined Small And Large Cell Lung Cancer

Mixed Small Cell And Squamous Cell Carcinoma Of Lung

Small Cell And Large Cell Carcinoma Of The Lung

Small Cell And Squamous Cell Carcinoma Of The Lung

Polymyositis

Pm - [Polymyositis]

Respiratory Failure

Acute Respiratory Failure

Chronic Respiratory Failure

Respiratory Insufficiency

Acute-On-Chronic Respiratory Failure

Acute And Chronic Respiratory Failure

Respiratory Insufficiency/Failure

Chronic Respiratory Disease

Respiratory Disease

Pulmonary Valve Insufficiency

Chronic Disease Of Respiratory System

Respiration Disorders

Respiratory Tract Diseases

Lung Failure Nos

Pulmonary Failure

Arf - [Acute Respiratory Failure]

Acute Respiratory Insufficiency

Acute Pulmonary Insufficiency

Acute Respiration Failure

Chronic Respiration Failure

Leptospirosis

Fort Bragg Fever

Weil Disease

Leptospirosis Icterohaemorrhagica

Nanukayami Fever

Canicola Fever

Hemorrhagic Jaundice

Mud Fever

Stuttgart Disease

Swamp Fever

Rat Catcher'S Yellows

Spirochetal Jaundice

Weil'S Disease

Cane-Cutter Fever

Icterohemorrhagic Fever

Rice-Field Fever

Swineherd'S Disease

Weil Syndrome

Nanukayami

Canine Leptospirosis

Equine Infectious Anemia

Leptospirosis Canicola

Fever Due To Leptospira Autumnalis

Gikiyami

Leptospira Interrogans Autumnalis Infection

Leptospira Interrogans Canicola Infection

Leptospira Interrogans Hebdomadis Infection

Leptospira Interrogans Pomona Infection

Nanukayami Disease

Pretibial Fever

Seven-Day Fever

Eia - [Equine Infectious Anaemia]

Leptospira Interrogans Infection

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Diabetes Mellitus, Non-Insulin-Dependent

Type 2 Diabetes

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Pericardial Effusion

Noninflammatory Pericardial Effusion

Pericardium Effusion

Subendocardial Myocardial Infarction
Spondylolisthesis

Slipped Vertebrae

Acquired Spondylolisthesis

Atrioventricular Block

Av Block

Raynaud Disease

Raynaud'S Disease

Raynaud Phenomenon

Raynaud'S Syndrome

Raynaud'S

Cold Fingers, Hereditary

Raynaud'S Phenomenon

Raynaud'S Disease/Phenomenon

Raynauds Syndrome

Raynauds Phenomenon

Secondary Raynaud'S Phenomenon

Raynaud Syndrome

Acute Kidney Tubular Necrosis

Acute Tubular Necrosis

Acute Renal Failure With Tubular Necrosis

Acute Tubule Necrosis

Acute Renal Failure With Lesion Of Tubular Necrosis

Atn - Acute Tubular Necrosis

Tubular Necrosis Acute

Kidney Tubular Necrosis, Acute

Acute Renal Tubular Necrosis

Acute Tubular Nephrosis

Ischaemic Acute Tubular Necrosis

Ischaemic Tubular Necrosis

Kidney Tubular Necrosis

Lower Nephron Nephrosis

Necrotising Renal Oedema

Renal Tubular Necrosis

Toxic Tubular Necrosis

Tubular Kidney Necrosis

Tubular Necrosis Nos

Tubular Nephrosis

Critical Illness Polyneuropathy

Polyneuropathy, Critical Illness

Cataract

Cataracts

Cat - [Cataract]

Cataract Form

Lens Opacity

Lens Opacities

Anuria

Suppression Of Urinary Secretion

Inferior Myocardial Infarction

Inferior Wall Myocardial Infarction

Myositis

Idiopathic Inflammatory Myopathy

Idiopathic Inflammatory Myositis

Iim

Imm

Idiopathic Inflammatory Myopathies

Myopathy, Familial Idiopathic Inflammatory

Inflammatory Disorder Of Muscle

Idiopathic Inflammatory Myopathy, Familial

Inflammatory Myopathy, Idiopathic

Myopathies Idiopathic Inflammatory

Familial Idiopathic Inflammatory Myopathy

Myocarditis

Myocardial Inflammation

Inflammatory Cardiomyopathy

Pleural Lipoma

Lipoma Of Pleura

Trichinosis

Trichinellosis

Human Trichinellosis

Trichiniasis

Trichinella Spiralis Infection

Infection With Trichinella

Trichinelliasis

Trichinella Spiralis Infestation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus PIK3C2A MGD MGI:1203729
Felis catus PIK3C2A VGNC VGNC:68850
Macaca mulatta PIK3C2A VGNC VGNC:75992
Canis familiaris PIK3C2A VGNC VGNC:44551
Rattus norvegicus PIK3C2A RGD RGD:1310389
Bos taurus PIK3C2A VGNC VGNC:106866