1. Gene
  2. Car12 - carbonic anhydrase 12 Gene

Car12 - carbonic anhydrase 12 Gene

中文名称:碳酸酐酶 12

种属: Rattus norvegicus

同用名: Ca12

基因 ID: 363085 | 基因类型: protein coding

关于 Car12

Primary_assembly 8: 67,274,359-67,330,440 forward strand.mRatBN7.2:CM026981.1

This gene has 3 transcripts (splice variants), 215 orthologues, 16 paralogues and is associated with 6 phenotypes.

功能概要

预测该基因编码的蛋白编码的蛋白可启动碳酸脱水酶活性。预计参与氯离子稳态和一碳代谢过程。预计是膜的组成部分。预计在质膜上有活性。该基因的人类直系同源物与孤立性多汗症有关。与人 CA12(碳酸酐酶 12)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable carbonate dehydratase activity. Predicted to be involved in chloride ion homeostasis and one-carbon metabolic process. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in isolated hyperchlorhidrosis. Orthologous to human CA12 (Carbonic Anhydrase 12). [provided by Alliance of Genome Resources, Apr 2022]

Car12 基因产物(1)

mRNA Protein Name
NM_001080756.2 NP_001074225.1 carbonic anhydrase 12 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in estrous cycle IEP
IEP: 通过表达模式推断
23869188 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
23869188 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
12923247 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

carbonic anhydrase 12

carbonic anyhydrase 12

membrane-bound carbonic anhydrase 12