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  2. IZUMO1R - IZUMO1 receptor, JUNO Gene

IZUMO1R - IZUMO1 receptor, JUNO Gene

中文名称:IZUMO1 受体,JUNO

种属: Homo sapiens

同用名: JUNO; FOLR4; Folbp3; FR-delta

基因 ID: 390243 | 基因类型: protein coding

关于 IZUMO1R

Cytogenetic location: 11q21 Genomic coordinates (GRCh38): 11:94,304,580-94,308,146 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

启用信号受体活动。预计参与细胞粘附;单次受精中精子与卵质膜的融合;和精卵识别。预测位于胞外区和质膜。预计是质膜外侧的锚定成分。 [由基因组资源联盟提供,2022 年 4 月]

Enables signaling receptor activity. Predicted to be involved in cell adhesion; fusion of sperm to egg plasma membrane involved in single fertilization; and sperm-egg recognition. Predicted to be located in extracellular region and plasma membrane. Predicted to be anchored component of external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IZUMO1R 基因产物(2)

mRNA Protein Name
NM_001199206.4 NP_001186135.1 sperm-egg fusion protein Juno precursor
NM_001393610.1 NP_001380539.1 sperm-egg fusion protein Juno precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24739963 GOA
enables signaling receptor activity IPI
IPI: 通过物理相互作用推断
24739963 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IZUMO1R 蛋白结构

Folate_rec

Folate_rec: Folate receptor family (26 - 201)

  • 0
  • 100
  • 200
  • 243 a.a.
蛋白主名 其他名称

sperm-egg fusion protein Juno

IZUMO1 receptor protein JUNO

重组 IZUMO1R 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77936 FOLR4 Protein, Human (HEK293, His) A6ND01-1 (G20-S228) ≥95%

关联疾病

疾病名称 别名
Subacute Leukemia
Biotin Deficiency

Biotin Deficiency Disease

B7 Deficiency

Biotan Vitamin Deficiency

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IZUMO1R RGD RGD:1585174
Mus musculus IZUMO1R MGD MGI:1929185
Bos taurus IZUMO1R VGNC VGNC:106788
Felis catus IZUMO1R VGNC VGNC:62992
Canis familiaris IZUMO1R VGNC VGNC:59053
Macaca mulatta IZUMO1R VGNC VGNC:101294
Others IZUMO1R NCBI