2. Gene
  3. Map4k5 - mitogen-activated protein kinase kinase kinase kinase 5 Gene

Map4k5 - mitogen-activated protein kinase kinase kinase kinase 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：丝裂原活化蛋白激酶激酶激酶激酶 5

种属: Mus musculus

同用名: KHS; GCKR; MAPKKKK5; 4432415E19Rik

基因 ID: 399510 | 基因类型: protein coding

关于 Map4k5

Chromosome 12: 69,850,524-69,939,974 reverse strand.GRCm39:CM001005.3

This gene has 10 transcripts (splice variants), 200 orthologues, 35 paralogues and is associated with 14 phenotypes. Ubiquitous expression in limb E14.5 (RPKM 9.4), bladder adult (RPKM 8.2) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 激酶结合活性和 MAP 激酶激酶活性。预计参与细胞内信号转导和蛋白磷酸化。预测作用于磷酸化上游或内部。预计位于细胞质中。在后肾和睾丸中表达。与人 MAP4K5（丝裂原活化蛋白激酶激酶 kinase kinase 5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity and MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytoplasm. Is expressed in metanephros and testis. Orthologous to human MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Map4k5 基因产物(1)

mRNA Protein Name
NM_201519.2 NP_958927.2 mitogen-activated protein kinase kinase kinase kinase 5

Map4k5 蛋白结构

STKc_MAP4K5

STKc_MAP4K5: cd06646 (9 - 276)

CNH

CNH: smart00036 (511 - 826)

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  • 847 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase kinase kinase kinase 5

MAPK/ERK kinase kinase kinase 5

MEK kinase kinase 5

MEKKK 5

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-147141 HS-276 Inhibitor 98.59% 否
HY-148063 DB0614 98.80% 否
HY-148061 DB1113 99.28% 否
HY-N3127 Orobol Inhibitor 99.28% 否
HY-RS08083 MAP4K5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08084 Map4k5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS08085 Map4k5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map4k5 NCBI NCBI:11183
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