KPNA7 - karyopherin subunit alpha 7 Gene

中文名称：karyopherin 亚基 alpha 7

种属: Homo sapiens

同用名: IPOA8

关于 KPNA7

功能概要

真核细胞中分子在细胞核和细胞质之间的运输是由核孔复合体 (NPC) 介导的，它由 60-100 种蛋白质组成。小分子 (高达 70 kD) 可以通过非选择性扩散穿过核孔，而大分子则通过活性过程运输。该基因编码的蛋白属于 importin alpha 家族，参与核蛋白导入，但与该家族其他成员相比表现出不同的核定位信号结合特异性。该基因的假基因已在 5 号染色体上定义。[RefSeq 提供，2016 年 7 月]

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to Other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016]