2. Gene
  3. MAP6 - microtubule associated protein 6 Gene

MAP6 - microtubule associated protein 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：微管相关蛋白 6

种属: Homo sapiens

同用名: STOP; MTAP6; MAP6-N; N-STOP

基因 ID: 4135 | 基因类型: protein coding

关于 MAP6

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:75,586,918-75,669,038 (from NCBI)

This gene has 4 transcripts (splice variants), 267 orthologues and 1 paralogue. Biased expression in brain (RPKM 4.6), testis (RPKM 2.8) and 13 other tissues.

功能概要

该基因编码微管相关蛋白。编码的蛋白质是钙调蛋白结合和钙调蛋白调节的蛋白质，参与微管稳定。已经为该基因鉴定了编码不同亚型的两个转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

MAP6 基因产物(2)

mRNA Protein Name
NM_033063.2 NP_149052.1 microtubule-associated protein 6 isoform 1
NM_207577.1 NP_997460.1 microtubule-associated protein 6 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24357581 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
24357581 GOA
involved in lysosome localization IMP
IMP: 通过突变表型推断
24357581 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in microtubule IDA
IDA: 通过直接分析推断
17210638 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
17210638 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MAP6 蛋白结构

STOP

STOP: STOP protein (3 - 166)

  • 0
  • 200
  • 400
  • 600
  • 813 a.a.
蛋白主名 其他名称

microtubule-associated protein 6

CTD-2530H12.7

关联疾病

疾病名称 别名
Cardia Cancer

Ca Cardia - Stomach

Malignant Neoplasm Of Cardia Of Stomach
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
Schizophrenia 1

SCZD1

Schizophrenia Susceptibility Locus, Chromosome 5-Related

Schizophrenia 1 With Or Without An Affective Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08086 MAP6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MAP6 VGNC VGNC:74640
Canis familiaris MAP6 VGNC VGNC:42986
Bos taurus MAP6 VGNC VGNC:54448
Mus musculus MAP6 MGD MGI:1201690
Felis catus MAP6 VGNC VGNC:82020
Rattus norvegicus MAP6 RGD RGD:61804
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