2. Gene
  3. ART3 - ADP-ribosyltransferase 3 (inactive) Gene

ART3 - ADP-ribosyltransferase 3 (inactive) Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ADP-核糖基转移酶 3 (无活性)

种属: Homo sapiens

同用名: ARTC3

基因 ID: 419 | 基因类型: protein coding

关于 ART3

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:76,011,190-76,112,786 (from NCBI)

This gene has 17 transcripts (splice variants), 582 orthologues and 3 paralogues. Biased expression in testis (RPKM 18.7) and heart (RPKM 6.2).

功能概要

该基因编码精氨酸特异性 ADP-核糖基转移酶。编码的蛋白质催化可逆反应，通过向精氨酸残基添加或去除 ADP-核糖来修饰蛋白质，从而调节修饰蛋白质的功能。 ADP-核糖基转移酶假基因位于 11 号染色体上。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2011 年 12 月]

This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

ART3 基因产物(16)

mRNA Protein Name
NM_001130016.3 NP_001123488.1 ecto-ADP-ribosyltransferase 3 isoform a precursor
NM_001130017.3 NP_001123489.1 ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001179.6 NP_001170.2 ecto-ADP-ribosyltransferase 3 isoform b precursor
NM_001377173.1 NP_001364102.1 ecto-ADP-ribosyltransferase 3 isoform d precursor
NM_001377174.1 NP_001364103.1 ecto-ADP-ribosyltransferase 3 isoform l precursor
NM_001377175.1 NP_001364104.1 ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001377176.1 NP_001364105.1 ecto-ADP-ribosyltransferase 3 isoform e precursor
NM_001377177.1 NP_001364106.1 ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377178.1 NP_001364107.1 ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377179.1 NP_001364108.1 ecto-ADP-ribosyltransferase 3 isoform g precursor
NM_001377180.1 NP_001364109.1 ecto-ADP-ribosyltransferase 3 isoform h precursor
NM_001377181.1 NP_001364110.1 ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377182.1 NP_001364111.1 ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377183.1 NP_001364112.1 ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377184.1 NP_001364113.1 ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377185.1 NP_001364114.1 ecto-ADP-ribosyltransferase 3 isoform k precursor

ART3 蛋白结构

ART

ART: NAD:arginine ADP-ribosyltransferase (29 - 252)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
蛋白主名 其他名称

ecto-ADP-ribosyltransferase 3

ADP-ribosyltransferase C2 and C3 toxin-like 3

重组 ART3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74409 ART3 Protein, Human (HEK293, His) AAH08397 (E27-S362) ≥95%

关联疾病

疾病名称 别名
Lumbosacral Lipoma
Hypermobility Of Coccyx

Coccygeal Hypermobility Syndrome

Hypermobility Of The Coccyx
Afferent Loop Syndrome

Afferent Limb Syndrome
Klippel-Feil Syndrome 3
Placenta Praevia

Placenta Previa

Haemorrhage From Placenta Previa

Placenta Previa Haemorrhage

Lateral Placenta

Low Implantation Of Placenta Nos Or With Haemorrhage

Total Placenta Previa

Total Placenta Praevia Nos Or With Haemorrhage

Placental Previa Haemorrhage

Pp - [Placenta Previa]

Placenta Previa Marginalis

Placenta Previa Partialis

Partial Placenta Previa

Placenta Previa Centralis

Low Implantation Of Placenta

Low Implantation Or Insertion Of Placenta

Low Insertion Of Placenta

Low Lying Placenta

Marginal Placenta

Marginal Placenta Praevia Nos Or With Haemorrhage

Marginal Placenta Previa

Marginal Placental Haemorrhage

Partial Placenta Praevia Nos Or With Haemorrhage
Kummell'S Disease

Traumatic Spondylopathy

Kummell Disease

Kummell'S Spondylitis

Kümmelll-Verneuil Disease

Kümmell Spondylitis

Kümmell Disease

Traumatic Spondylosis
Brown-Sequard Syndrome

Brown-Squard Syndrome

Hemicord Syndrome

Hemiparaplegic Syndrome

Hemispinal Cord Syndrome

Brown-Séquard Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01045 ART3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ART3 MGD MGI:1202729
Rattus norvegicus ART3 RGD RGD:628833
Felis catus ART3 VGNC VGNC:68318
Bos taurus ART3 VGNC VGNC:26180
Canis familiaris ART3 VGNC VGNC:38148
Macaca mulatta ART3 VGNC VGNC:70025
Others ART3 NCBI
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