2. Gene
  3. MFAP3 - microfibril associated protein 3 Gene

MFAP3 - microfibril associated protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：微纤维相关蛋白 3

种属: Homo sapiens

基因 ID: 4238 | 基因类型: protein coding

关于 MFAP3

Cytogenetic location: 5q33.2 Genomic coordinates (GRCh38): 5:154,038,967-154,057,450 (from NCBI)

This gene has 14 transcripts (splice variants), 187 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 9.1), urinary bladder (RPKM 9.1) and 25 other tissues.

功能概要

预测位于细胞外区域。预计在细胞质中有活性；核;和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be located in extracellular region. Predicted to be active in cytoplasm; nucleus; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MFAP3 基因产物(3)

mRNA Protein Name
NM_001135037.2 NP_001128509.1 microfibril-associated glycoprotein 3 isoform 2
NM_001242336.2 NP_001229265.1 microfibril-associated glycoprotein 3 isoform 1 precursor
NM_005927.5 NP_005918.1 microfibril-associated glycoprotein 3 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MFAP3 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (61 - 130)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
蛋白主名 其他名称

microfibril-associated glycoprotein 3

microfibrillar associated protein 3

MFAP3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MFAP3 P55082 GRIP1 Homo sapiens Q9Y3R0-3
Validated Y2H
32296183
种属内
MFAP3 P55082 GRIP1 Homo sapiens Q9Y3R0-3
Y2H Array
32296183
种属内
MFAP3 P55082 GRIP1 Homo sapiens Q9Y3R0-3
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 MFAP3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77085 MFAP3 Protein, Human (HEK293, Fc) P55082-1 (A19-M147) ≥95%

关联疾病

疾病名称 别名
Lutembacher'S Syndrome

Lutembacher Syndrome

Lutembacher'S Anomaly
Contractural Arachnodactyly, Congenital

Congenital Contractural Arachnodactyly

Beals Syndrome

CCA

Beals-Hecht Syndrome

Distal Arthrogryposis Type 9

Arthrogryposis, Distal, Type 9

Da9

Arachnodactyly, Contractural Beals Type

Contractures, Multiple With Arachnodactyly

Ear Anomalies-Contractures-Dysplasia Of Bone With Kyphoscoliosis

Arthrogyroposis, Distal, Type 9

Distal Arthrogyropsis Type 9

Cca Syndrome

Arachnodactyly
Yellow Nail Syndrome

Yns

Lymphedema And Yellow Nails

Lymphedema With Yellow Nails

Lymphedema-Yellow Nails

LYYN

Hereditary Lymphedema And Yellow Nails

Hereditary Lymphoedema And Yellow Nails
Isolated Ectopia Lentis

Familial Ectopia Lentis

Ectopia Lentis

Ectopia Lentis Syndrome

Lens Subluxation

Iel

Congenital Ectopia Lentis

Subluxation Of Lens

Ectopia Lentis, Isolated

Ectopia Lentis Isolated
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08377 MFAP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus MFAP3 VGNC VGNC:68240
Bos taurus MFAP3 VGNC VGNC:50216
Macaca mulatta MFAP3 VGNC VGNC:74709
Rattus norvegicus MFAP3 RGD RGD:1359463
Canis familiaris MFAP3 VGNC VGNC:43188
Mus musculus MFAP3 MGD MGI:1924068
Others MFAP3 NCBI
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