1. Gene
  2. MT1E - metallothionein 1E Gene

MT1E - metallothionein 1E Gene

中文名称:金属硫蛋白 1E

种属: Homo sapiens

同用名: MT1; MTD; MT-1E; MT-IE

基因 ID: 4493 | 基因类型: protein coding

关于 MT1E

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,625,781-56,627,112 (from NCBI)

This gene has 3 transcripts (splice variants), 186 orthologues and 11 paralogues. Broad expression in liver (RPKM 106.4), small intestine (RPKM 103.9) and 20 other tissues.

功能概要

预测可启用锌离子结合活性。参与细胞对镉离子的反应和细胞对锌离子的反应。位于细胞质和细胞核中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable zinc ion binding activity. Involved in cellular response to cadmium ion and cellular response to zinc ion. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT1E 基因产物(2)

mRNA Protein Name
NM_001363555.2 NP_001350484.1 metallothionein-1E isoform 1
NM_175617.4 NP_783316.2 metallothionein-1E isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cadmium ion IEP
IEP: 通过表达模式推断
16827180 GOA
involved in cellular response to zinc ion IEP
IEP: 通过表达模式推断
8119276 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
8619255 GOA
located in nucleus IDA
IDA: 通过直接分析推断
8619255 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MT1E 蛋白结构

Metallothio

Metallothio: Metallothionein (1 - 61)

  • 0
  • 61 a.a.
蛋白主名 其他名称

metallothionein-1E

metallothionein 1E (functional)

MT1E 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MT1E P04732 CCDC57 Homo sapiens Q2TAC2-2 32296183
种属内
MT1E P04732 CCDC57 Homo sapiens Q2TAC2-2 32296183
种属内
MT1E P04732 CCDC57 Homo sapiens Q2TAC2-2 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Frontometaphyseal Dysplasia 1

FMD1

Fmd

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Deficiency Anemia

Anemia

Deficiency Anemias

Anaemia

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus MT1E MGD MGI:97171