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  2. NINJ1 - ninjurin 1 Gene

NINJ1 - ninjurin 1 Gene

中文名称:忍术 1

种属: Homo sapiens

同用名: NIN1; NINJURIN

基因 ID: 4814 | 基因类型: protein coding

关于 NINJ1

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:93,121,496-93,134,251 (from NCBI)

This gene has 5 transcripts (splice variants), 231 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 105.7), placenta (RPKM 42.4) and 24 other tissues.

功能概要

神经损伤后,背根神经节神经元和雪旺细胞中的忍者蛋白都会上调 (Araki 和 Milbrandt,1996 [PubMed 8780658]) 。它展示了嗜同性粘附分子的特性,并促进原代培养的背根神经节神经元的神经突长出。[OMIM 提供,2009 年 8 月]

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009]

NINJ1 基因产物(1)

mRNA Protein Name
NM_004148.4 NP_004139.2 ninjurin-1

NINJ1 蛋白结构

Ninjurin

Ninjurin: Ninjurin (37 - 140)

  • 0
  • 100
  • 152 a.a.
蛋白主名 其他名称

ninjurin-1

nerve injury-induced protein-1

NINJ1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NINJ1 Q92982 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra NINJ1 Q92982 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra NINJ1 Q92982 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra NINJ1 Q92982 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra NINJ1 Q92982 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra NINJ1 Q92982 CD200R1 Homo sapiens Q8TD46-4
Y2H Array
32296183
Intra NINJ1 Q92982 CD200R1 Homo sapiens Q8TD46-4
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 CEACAM3 Homo sapiens P40198
Y2H Array
32296183
Intra NINJ1 Q92982 CEACAM3 Homo sapiens P40198
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Validated Y2H
32296183
Intra NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra NINJ1 Q92982 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra NINJ1 Q92982 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra NINJ1 Q92982 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Validated Y2H
32296183
Intra NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Y2H Array
32296183
Intra NINJ1 Q92982 LIME1 Homo sapiens Q9H400
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 FCGR1A Homo sapiens P12314
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 FCGR1A Homo sapiens P12314
Y2H Array
32296183
Intra NINJ1 Q92982 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra NINJ1 Q92982 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 SGCB Homo sapiens Q16585
Y2H Array
32296183
Intra NINJ1 Q92982 SGCB Homo sapiens Q16585
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
Intra NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 TIMMDC1 Homo sapiens Q9NPL8
Y2H Array
32296183
Intra NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra NINJ1 Q92982 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra NINJ1 Q92982 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spondylometaphyseal Dysplasia With Corneal Dystrophy

SMDCD

Spondylometaphyseal Dysplasia-Corneal Dystrophy Syndrome

Smd-Corneal Dystrophy Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris NINJ1 VGNC VGNC:43811
Macaca mulatta NINJ1 VGNC VGNC:75350
Rattus norvegicus NINJ1 RGD RGD:3179
Mus musculus NINJ1 MGD MGI:1196617
Bos taurus NINJ1 VGNC VGNC:32078
Felis catus NINJ1 VGNC VGNC:97527
Others NINJ1 NCBI