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  2. Smyd3 - SET and MYND domain containing 3 Gene

Smyd3 - SET and MYND domain containing 3 Gene

中文名称:含 SET 和 MYND 域 3

种属: Rattus norvegicus

基因 ID: 498295 | 基因类型: protein coding

关于 Smyd3

Primary_assembly 13: 90,709,270-91,266,253 reverse strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 231 orthologues, 5 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 59.6), Kidney (RPKM 4.4) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动 RNA 聚合酶 II 复合物结合活性; RNA 聚合酶 II 转录调节区序列特异性 DNA 结合活性;和组蛋白-赖氨酸 N-甲基转移酶活性。预计在几个过程的上游或内部起作用,包括细胞对地塞米松刺激的反应;核小体组装;和蛋白质磷酸化的调节。预计位于胞质溶胶和核质中。与人类 SMYD3 同源(SET 和 MYND 结构域包含 3)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable RNA polymerase II complex binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and histone-lysine N-methyltransferase activity. Predicted to act upstream of or within several processes, including cellular response to dexamethasone stimulus; nucleosome assembly; and regulation of protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Orthologous to human SMYD3 (SET and MYND domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Smyd3 基因产物(1)

mRNA Protein Name
NM_001025762.1 NP_001020933.1 histone-lysine N-methyltransferase SMYD3

Smyd3 蛋白结构

SET_SMYD3

SET_SMYD3: cd19203 (4 - 267)

zf-MYND

zf-MYND: pfam01753 (48 - 86)

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  • 428 a.a.
蛋白主名 其他名称

histone-lysine N-methyltransferase SMYD3

SET and MYND domain-containing protein 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smyd3 NCBI NCBI:64754