2. Gene
  3. Nod1 - nucleotide-binding oligomerization domain containing 1 Gene

Nod1 - nucleotide-binding oligomerization domain containing 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含核苷酸结合寡聚化结构域 1

种属: Rattus norvegicus

同用名: RGD1562269

基因 ID: 500133 | 基因类型: protein coding

关于 Nod1

Primary_assembly 4: 84,060,880-84,111,404 reverse strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 201 orthologues, 21 paralogues and is associated with 11 phenotypes. Biased expression in Lung (RPKM 116.8), Spleen (RPKM 113.4) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动 CARD 域绑定活动；模式识别受体活动；和蛋白质同二聚化活性。参与细胞死亡的正调控；细胞因子产生的正调节；和一氧化氮合酶活性的正调节。预测位于基底外侧质膜；胞质溶胶；和吞噬泡。预测为质膜的锚定成分。该基因的人类直系同源物与哮喘有关。与人 NOD1 同源（包含 1 的核苷酸结合寡聚化结构域）。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable CARD domain binding activity; pattern recognition receptor activity; and protein homodimerization activity. Involved in positive regulation of cell death; positive regulation of cytokine production; and positive regulation of nitric-oxide synthase activity. Predicted to be located in basolateral plasma membrane; cytosol; and phagocytic vesicle. Predicted to be anchored component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Nod1 基因产物(1)

mRNA Protein Name
NM_001109236.1 NP_001102706.1 nucleotide-binding oligomerization domain-containing protein 1
蛋白主名 其他名称

nucleotide-binding oligomerization domain-containing protein 1

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100691 NOD-IN-1 Inhibitor 99.56% 否
HY-18639 Nodinitib-1 Inhibitor 99.94% 否
HY-168023 NOD1-IN-1 Inhibitor / 否
HY-170447 NOD1 antagonist-2 Antagonist / 否
HY-146034 NOD1/2 antagonist-1 Antagonist / 否
HY-163274 NOD1 antagonist-1 Antagonist / 否
HY-159965 NOD1-RIPK2-IN-1 Inhibitor / 否
HY-168024 NOD1/2-IN-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nod1 NCBI NCBI:10392
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