Rps6ka3 - ribosomal protein S6 kinase A3 Gene

中文名称：核糖体蛋白 S6 激酶 A3

种属: Rattus norvegicus

同用名: RGD1563860

关于 Rps6ka3

功能概要

预测该基因编码的蛋白可使半胱氨酸型内肽酶抑制剂活性参与细胞凋亡过程；蛋白激酶结合活性；和核糖体蛋白 S6 激酶活性。预计参与多个过程，包括参与细胞凋亡过程的半胱氨酸型内肽酶活性的负调控；肽基丝氨酸磷酸化；和对脂多糖的反应。预测位于胞质溶胶和核仁中。预计在细胞质和核质中有活性。该基因的人类直系同源物与 Coffin-Lowry 综合征有关；智力残疾;和非综合征性 X 连锁智力障碍 19. 与人类 RPS6KA3（核糖体蛋白 S6 激酶 A3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein kinase binding activity; and ribosomal protein S6 kinase activity. Predicted to be involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; peptidyl-serine phosphorylation; and response to lipopolysaccharide. Predicted to be located in cytosol and nucleolus. Predicted to be active in cytoplasm and nucleoplasm. Human ortholog(s) of this gene implicated in Coffin-Lowry syndrome; intellectual disability; and non-syndromic X-linked intellectual disability 19. Orthologous to human RPS6KA3 (ribosomal protein S6 kinase A3). [provided by Alliance of Genome Resources, Apr 2022]