1. Gene
  2. DPRX - divergent-paired related homeobox Gene

DPRX - divergent-paired related homeobox Gene

中文名称:发散配对相关同源框

种属: Homo sapiens

基因 ID: 503834 | 基因类型: protein coding

关于 DPRX

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:53,601,114-53,637,014 (from NCBI)

This gene has 1 transcript (splice variant), 34 orthologues and 50 paralogues. Low expression observed in reference dataset.

功能概要

同源框基因编码 DNA 结合蛋白,其中许多被认为与早期胚胎发育有关。同源框基因编码 60 至 63 个氨基酸的 DNA 结合域,称为同源域。该基因是 DPRX 同源框基因家族的成员。尚未发现该基因 mRNA 表达的证据。已发现多个相关的加工假基因,它们被认为反映了该基因在种系或胚胎细胞中的表达。[RefSeq 提供,2008 年 7 月]

Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 Amino acids referred to as the homeodomain. This gene is a member of the DPRX homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]

DPRX 基因产物(1)

mRNA Protein Name
NM_001012728.2 NP_001012746.1 divergent paired-related homeobox
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DPRX 蛋白结构

Homeobox

Homeobox: Homeobox domain (18 - 73)

  • 0
  • 100
  • 191 a.a.
蛋白主名 其他名称

divergent paired-related homeobox

关联疾病

疾病名称 别名
Non-Gestational Choriocarcinoma

Choriocarcinoma, Non-Gestational

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma