CLEC4A - C-type lectin domain family 4 member A Gene

中文名称：C 型凝集素结构域家族 4 成员 A

种属: Homo sapiens

同用名: DCIR; LLIR; CD367; DDB27; hDCIR; CLECSF6; HDCGC13P

关于 CLEC4A

功能概要

该基因编码 C 型凝集素/C 型凝集素样结构域 (CTL/CTLD) 超家族的成员。该家族的成员具有共同的蛋白质折叠并具有多种功能，例如细胞粘附、细胞间信号传导、糖蛋白转换以及在炎症和免疫反应中的作用。编码的 2 型跨膜蛋白可能在炎症和免疫反应中发挥作用。已经为该基因鉴定了编码不同亚型的多个转录物变体。该基因与自然杀伤基因复合区 12p13 染色体上的其他 CTL/CTLD 超家族成员密切相关。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to Other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]